Actively Recruiting
Multimodal Imaging Assessment of the Inflammatory Atheromatous Plaque
Led by University of Lausanne Hospitals · Updated on 2024-06-20
20
Participants Needed
1
Research Sites
661 weeks
Total Duration
On this page
Sponsors
U
University of Lausanne Hospitals
Lead Sponsor
S
Swiss Heart Foundation
Collaborating Sponsor
AI-Summary
What this Trial Is About
The present study aims at assessing the ability of 68Ga-NODAGA-RGD PET/CT for the detection of inflammatory atheromatous plaques in the carotid arteries, compared to 18F-FDG PET/CT, MRI and US and to determine the contribution of each imaging technique. Current gold standard for inflammation is histopathology. Hypothesis : 68Ga-NODAGA-RGD might give a better initial evaluation of patients with atheromatous plaques in the carotid artery eligible for endarterectomy.
CONDITIONS
Official Title
Multimodal Imaging Assessment of the Inflammatory Atheromatous Plaque
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 85 years or younger
- Karnofsky performance score of 80% or higher
- Patient must be scheduled for carotid endarterectomy
- Signed informed consent form
You will not qualify if you...
- Surgery indication other than endarterectomy within less than 14 days
- Contraindication to surgery
- Contraindication to MRI
- Contraindication to gadolinium injection (stage 4 or 5 kidney insufficiency, GFR less than 30 ml/min/1.73m2)
- Pregnancy or breastfeeding
- Lack of discernment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Centre Hospitalier Universitaire Vaudois
Lausanne, Canton of Vaud, Switzerland, 1011
Actively Recruiting
Research Team
J
John O. Prior, PhD, MD
CONTACT
E
Emmanuel Deshayes, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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