Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT03967834

Multimodal Immune Characterization of RAre Soft Tissue Sarcoma - MIRAS Project From SARRA (SARcome RAre) Project of the French Sarcoma Group

Led by Institut Claudius Regaud · Updated on 2026-02-10

400

Participants Needed

20

Research Sites

518 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This trial is a translational, open-label, multi-sites, prospective and retrospective cohort study of 500 patients aimed at clinical and biological characterization of sarcoma of rare subtype. 400 patients will be included in this prospective cohort study; they will be identified in the investigating centers in the context of either routine care or a clinical study protocol. Retrospective cases of patients (100 cases in total) will be identified in all centers through the GSF/GETO clinical databases already setted up (including the clinical base Conticabase).

CONDITIONS

Official Title

Multimodal Immune Characterization of RAre Soft Tissue Sarcoma - MIRAS Project From SARRA (SARcome RAre) Project of the French Sarcoma Group

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older at the time of study entry
  • Diagnosis confirmed by RRePS network of one of these rare sarcoma subtypes: Clear Cell Sarcoma, Epithelioid Sarcoma, Perivascular Epithelioid Cell Neoplasm, Desmoplastic Small Round Cell Tumor, Malignant Solitary Fibrous Tumor, Alveolar Soft Part Sarcoma, Epithelioid Hemangioendothelioma, Low-Grade Fibromyxoid Sarcoma, or Sclerosing Epithelioid Fibrosarcoma
  • Localized, locally advanced, or metastatic disease
  • For localized disease, treatment not started before inclusion except surgical excision
  • For metastatic disease, a new systemic treatment line planned before inclusion
  • Followed within standard care or clinical trial at the center
  • Archived tumor specimen available from initial diagnosis before treatment
  • Disease measurable or not as per RECIST 1.1
  • ECOG performance status between 0 and 3
  • Able and willing to give informed consent before any study procedures
  • Affiliated with Social Health Insurance in France
Not Eligible

You will not qualify if you...

  • Diagnosis of any other soft tissue sarcoma histotypes
  • Any condition preventing procedures required by the study protocol
  • Known positive test for hepatitis B, hepatitis C, HIV, or AIDS
  • Psychological, familial, geographic, or social factors preventing informed consent or study compliance as judged by investigator
  • Pregnant or breastfeeding women
  • Patients legally deprived of freedom or under guardianship

AI-Screening

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Trial Site Locations

Total: 20 locations

1

Chu Besancon - Site Jean Minjoz

Besançon, France, 25000

Actively Recruiting

2

Institut Bergonié

Bordeaux, France

Actively Recruiting

3

Centre Jean Perrin

Clermont-Ferrand, France, 63011

Actively Recruiting

4

Centre Georges François Leclerc

Dijon, France

Not Yet Recruiting

5

Centre Oscar Lambret

Lille, France, 59020

Actively Recruiting

6

Chu Dupuytren

Limoges, France

Actively Recruiting

7

Centre Leon Berard

Lyon, France, 69008

Actively Recruiting

8

Institut Paoli-Calmettes

Marseille, France, 13009

Withdrawn

9

Chu de Marseille - Hopital de La Timone

Marseille, France

Actively Recruiting

10

Centre Antoine Lacassagne

Nice, France, 06189

Actively Recruiting

11

Hôpital Cochin - Site Port-Royal

Paris, France

Actively Recruiting

12

Institut Curie

Paris, France

Actively Recruiting

13

Chu Poitiers

Poitiers, France

Actively Recruiting

14

Institut Godinot

Reims, France

Actively Recruiting

15

Centre Eugene Marquis

Rennes, France

Actively Recruiting

16

Institut de Cancerologie de L'Ouest - Site Rene Gauducheau

Saint-Herblain, France, 44805

Withdrawn

17

Hôpitaux Universitaires de Strasbourg

Strasbourg, France

Actively Recruiting

18

Institut Universitaire du Cancer Toulouse - Oncopole

Toulouse, France

Actively Recruiting

19

Institut de Cancerologie de Lorraine

Vandœuvre-lès-Nancy, France, 54519

Actively Recruiting

20

Institut Gustave Roussy

Villejuif, France, 94805

Withdrawn

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Research Team

T

Thibaud VALENTIN

CONTACT

F

Frédéric CHIBON

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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