Study of Brain Monitoring Techniques and Biomarkers During the First Week After Acute Brain Injury in Neurocritical Care

What this Trial Is About

Researchers are investigating acute brain injuries such as subarachnoidal hemorrhage, intracranial hypertension, and acute trauma brain injury. The study aims to understand brain pathophysiology during the first week after injury by exploring brain oxygen use, metabolic disorders, and electrical activity through various monitoring techniques. The goal is to identify valuable biomarkers using multimodal monitoring to better track brain function and prevent delayed injuries. The study involves observing patients admitted to neurocritical care who are monitored with the CNS MOBERGae system. Researchers will study the correlation between different cerebral autoregulation indexes like PRx, ORx, and Cox, and also analyze EEG patterns to detect early prognostic changes. Monitoring occurs from 1 to 15 days after the acute brain injury. Participants will be closely observed in the neurocritical care unit with continuous multimodal monitoring. The main outcome measured is the correlation between ORx and PRx autoregulation indexes. No experimental treatments are given as this is an observational study. Data collection includes neurological exams and monitoring brain activity and oxygen levels. The study duration covers the first week post injury with ongoing monitoring up to 15 days.

Multimodal Monitoring Study in Neuro Critical Care