Actively Recruiting
Multimodal Musical Stimulation for Healthy Neurocognitive Aging
Led by Northeastern University · Updated on 2025-07-10
100
Participants Needed
1
Research Sites
263 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a Stage I randomized, sham-controlled trial on the effects of multimodal musical stimulation on working memory in aging. Neurologically healthy older and younger adults will be tested on working memory and electroencephalography in the first randomized controlled trial of music as a form of brain stimulation, with multimodal musical stimulation and control stimulation conditions. Results will test the causal role of oscillatory mechanisms of the brain on cognition, and will lay the groundwork to the first musical, neurophysiologically targeted, brain-stimulation device for reversing cognitive decline in aging.
CONDITIONS
Official Title
Multimodal Musical Stimulation for Healthy Neurocognitive Aging
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Normal or corrected-to-normal vision
- No more than mild hearing loss
- No recent history of neurological or psychiatric disorders, including mood disorders or use of medications that may affect cognition or responsiveness to music
You will not qualify if you...
- Moderate or severe hearing loss (40+ dB)
- Visual impairment (including color blindness) that cannot be corrected with glasses or contacts
- Recently changed dosage of cholinesterase inhibitors or psychotropic medication
- Recent history of psychotic or schizophrenic episodes
- Major neurologic diagnosis or other condition that might impair cognition or confound assessments (dementia, ADRD; Parkinson's disease, stroke, brain injury, epilepsy, or recent cardiovascular or neurovascular event)
- Recent history of serious physical trauma or diagnosis of serious chronic health condition requiring medical treatment and monitoring .
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Northeastern University
Boston, Massachusetts, United States, 02115
Actively Recruiting
Research Team
C
Corinna Parrish
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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