Actively Recruiting
Multimodal PET Imaging in the Diagnosis and Treatment of Pelvic Tumors in Endometrial Cancer
Led by Peking Union Medical College Hospital · Updated on 2025-01-14
30
Participants Needed
1
Research Sites
82 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to explore the use of gallium 68 labeled-fibroblast activation protein inhibitor-04 (68Ga-FAPI-04) Positron Emission Tomography (PET) imaging in women with endometrial cancer. The study compares 68Ga-FAPI-04 PET with other imaging agents to evaluate its advantages in diagnosing this condition. It involves analyzing diagnostic effectiveness by comparing 68Ga-FAPI-04 PET with Fluorine-18 labeled Fluorodeoxyglucose (18F-FDG) PET imaging. Participants undergo three types of imaging examinations: 68Ga-FAPI-04 PET/Computed Tomography (PET/CT), PET/Magnetic Resonance Imaging (PET/MRI), and 18F-FDG PET/CT. The 68Ga-FAPI-04 agent is given intravenously at a dose based on patient weight, followed by whole-body scans 30 to 60 minutes later. The 18F-FDG PET/CT scan is performed within one week before or after the other imaging tests. After imaging, patients have surgical removal of the tumor and suspicious lymph nodes to obtain pathological results. During the study, medical history and necessary laboratory tests are collected. Researchers analyze and compare the diagnostic value of all imaging methods, focusing on tumor size and SUVmax outcomes, tracked over approximately one year. The study monitors patients' diagnostic responses and surgical findings to assess the imaging techniques' effectiveness in endometrial cancer diagnosis and treatment.
CONDITIONS
Official Title
Multimodal PET Imaging in the Diagnosis and Treatment of Pelvic Tumors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 70 years
- Willing to provide written informed consent
- Able to attend follow-up visits
- Eligible for surgery or biopsy to obtain final pathological results
You will not qualify if you...
- Pregnant or breastfeeding women
- Conditions that prevent further diagnosis or treatment due to severity
- Any contraindications to magnetic resonance imaging (MRI)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Peking Union Medical College Hospital
Beijing, Beijing Municipality, China, 100730
Actively Recruiting
Research Team
Z
Zhaoxia huang, B.S.
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here