Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT04520737

Multimodal Prehabilitation During Chemotherapy in Patients With Colorectal Liver Metastases

Led by Institut Investigacio Sanitaria Pere Virgili · Updated on 2024-07-01

84

Participants Needed

1

Research Sites

308 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Liver resection is the only curative treatment for patients with colorectal liver metastases (CRLM). Most patients undergo chemotherapy (CT) before liver surgery. CT objectively decreases patient functional capacity. It has already been demonstrated that a structured training program carried out during the 4 weeks following CT, while the patient is waiting for liver resection, is able to return the functional capacity to baseline levels. Despite this, multimodal prehabilitation programs (MPP) during preoperative CT have not been evaluated or implemented. The aim of this study is to investigate whether a 16-week MPP applied during and following CT in CRLM patients will result in a significant increase in physical fitness when compared to those that undergo MPP only during the 4-weeks, between the end of CT and liver resection.

CONDITIONS

Official Title

Multimodal Prehabilitation During Chemotherapy in Patients With Colorectal Liver Metastases

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 65 18 years
  • Written informed consent obtained from subject to participate in the study.
Not Eligible

You will not qualify if you...

  • Age <18 years
  • ASA health class status IV-V
  • Mental conditions or disabling orthopedic and neuromuscular disease that prevent physical exercise or may compromise adherence to the program
  • Medical contraindication to perform exercise
  • Inability to obtain informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hospital Universitari de Tarragona Joan XXIII

Tarragona, Spain, 43005

Actively Recruiting

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Research Team

L

Laia Estalella, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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