Actively Recruiting

Phase Not Applicable
Age: 21Years +
All Genders
NCT07390071

Multimodal Telerehabilitation in Patients Undergoing CAR-T Cell Immunotherapy

Led by University of Utah · Updated on 2026-02-05

40

Participants Needed

1

Research Sites

174 weeks

Total Duration

On this page

Sponsors

U

University of Utah

Lead Sponsor

U

United States Department of Defense

Collaborating Sponsor

AI-Summary

What this Trial Is About

The proposed multimodal telerehabilitation model allows a rehabilitation therapy team to set up individualized rehabilitation plans using a web-based care management portal and monitor patient progress online. Patients at home follow a safe and effective personalized exercise and nutrition plan guided by interactive touch-screen technology combined with behavioral counseling, social support, and interactive education and empowerment. The design of the telerehabilitation system is based on the cloud-based Internet-of-Things architecture allowing real-time monitoring of cardiovascular parameters and exercise performance. The patient's level of exertion during exercise is automatically identified by a validated AI-driven algorithm supporting exercise safety and efficacy. The ultimate goal of this pilot feasibility project is to establish the extent of the impact of the proposed patient-centered cancer telerehabilitation model on disease-specific quality of life, and functional and symptom outcomes and to obtain sufficient evidence for a definitive randomized clinical trial evaluating this approach in a multi-center study.

CONDITIONS

Official Title

Multimodal Telerehabilitation in Patients Undergoing CAR-T Cell Immunotherapy

Who Can Participate

Age: 21Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age >21 years
  • Confirmed diagnosis of lymphoma or myeloma
  • Planned commercial FDA-approved CAR-T therapy at least 4 weeks after enrollment
  • Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 2
  • Access to a working telephone line or cell phone at home
Not Eligible

You will not qualify if you...

  • Unstable angina, uncontrolled hypertension, recent heart attack, pacemakers, painful or unstable bone metastases, or recent bone fractures
  • Currently engaged in a regular exercise rehabilitation program
  • Plans to relocate within the next 6 months
  • Participation in another clinical trial

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Huntsman Cancer Institute at University of Utah

Salt Lake City, Utah, United States, 84112

Actively Recruiting

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Research Team

A

Aileen Gabriel

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

PREVENTION

Number of Arms

1

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