Actively Recruiting
Multimodal Telerehabilitation in Patients Undergoing CAR-T Cell Immunotherapy
Led by University of Utah · Updated on 2026-02-05
40
Participants Needed
1
Research Sites
174 weeks
Total Duration
On this page
Sponsors
U
University of Utah
Lead Sponsor
U
United States Department of Defense
Collaborating Sponsor
AI-Summary
What this Trial Is About
The proposed multimodal telerehabilitation model allows a rehabilitation therapy team to set up individualized rehabilitation plans using a web-based care management portal and monitor patient progress online. Patients at home follow a safe and effective personalized exercise and nutrition plan guided by interactive touch-screen technology combined with behavioral counseling, social support, and interactive education and empowerment. The design of the telerehabilitation system is based on the cloud-based Internet-of-Things architecture allowing real-time monitoring of cardiovascular parameters and exercise performance. The patient's level of exertion during exercise is automatically identified by a validated AI-driven algorithm supporting exercise safety and efficacy. The ultimate goal of this pilot feasibility project is to establish the extent of the impact of the proposed patient-centered cancer telerehabilitation model on disease-specific quality of life, and functional and symptom outcomes and to obtain sufficient evidence for a definitive randomized clinical trial evaluating this approach in a multi-center study.
CONDITIONS
Official Title
Multimodal Telerehabilitation in Patients Undergoing CAR-T Cell Immunotherapy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age >21 years
- Confirmed diagnosis of lymphoma or myeloma
- Planned commercial FDA-approved CAR-T therapy at least 4 weeks after enrollment
- Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 2
- Access to a working telephone line or cell phone at home
You will not qualify if you...
- Unstable angina, uncontrolled hypertension, recent heart attack, pacemakers, painful or unstable bone metastases, or recent bone fractures
- Currently engaged in a regular exercise rehabilitation program
- Plans to relocate within the next 6 months
- Participation in another clinical trial
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Huntsman Cancer Institute at University of Utah
Salt Lake City, Utah, United States, 84112
Actively Recruiting
Research Team
A
Aileen Gabriel
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
PREVENTION
Number of Arms
1
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