Actively Recruiting
Multimodal Ultrasound in DBD Kidneys for Predicting Early Postoperative Renal Insufficiency Risk
Led by Bei Wang · Updated on 2025-07-29
27
Participants Needed
1
Research Sites
64 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The objective of this observational study is to investigate the multimodal ultrasound parameters of kidneys from brain-dead organ donors prior to donation, in order to construct a predictive model for assessing the risk of early transplant renal dysfunction after kidney transplantation in recipients. The primary question this study aims to address is: Can multimodal ultrasound data from brain-dead organ donor kidneys accurately predict early post-transplant renal dysfunction? Ultrasonography, as a routine examination before organ donation, will be utilized, and the study results will be concluded within one year after participation in this study.
CONDITIONS
Official Title
Multimodal Ultrasound in DBD Kidneys for Predicting Early Postoperative Renal Insufficiency Risk
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Recipient study participants must be 18 years or older
- Underwent allogeneic kidney transplantation at this hospital
- Signed an informed consent form
- Donor study participants must be brain-dead organ donors
- Organ donation completed at the First Affiliated Hospital of Shandong First Medical University
- Brain death confirmed by deep coma, absence of brainstem reflexes, no spontaneous respiration, and at least two confirmatory tests
- Standard Criteria Donor (SCD) aged 10-39 years with cause of death unrelated to cerebrovascular disease, serum creatinine <133 µmol/L, and no history of hypertension
- Expanded Criteria Donor (ECD) aged over 60 years, or aged 50-59 years with two of the following: cause of death related to cerebrovascular disease, serum creatinine <133 µmol/L, history of hypertension
- Signed informed consent form
You will not qualify if you...
- Recipient study participants with multiple kidney transplants
- Patients with follow-up duration less than 1 year
- Patients with irreversible loss of graft function due to post-operative complications such as rejection, thrombosis, anastomotic stenosis, or infection
- Donor study participants with severe primary renal diseases including hypertensive nephropathy, diabetic nephropathy, or renal tumors
- Cases with unavailable ultrasound imaging data due to excessive respiratory motion or obesity affecting image quality
- Individuals with allergic predisposition
AI-Screening
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Trial Site Locations
Total: 1 location
1
The First Affiliated Hospital of Shandong First Medical University
Jinan, Shandong, China, 250000
Actively Recruiting
Research Team
B
Bei Wang
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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