Actively Recruiting
Multiple-Visit RCT in Teeth With SAP: Interappointment Dressing or Not?
Led by Aristotle University Of Thessaloniki · Updated on 2026-02-10
110
Participants Needed
1
Research Sites
104 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of the study is to evaluate the effectiveness of calcium hydroxide as an intracanal medicament in the clinical and radiographic healing of periapical tissues in teeth diagnosed with symptomatic apical periodontitis. This evaluation will be conducted after multiple visit endodontic treatment. The follow-up sessions will be programmed from 6 to 24 months postoperatively. Postoperative pain will also be considered as a secondary outcome. Participants will be asked to rate their pain level on a numerical scale from 0 to10 before and after each session of endodontic treatment. Additionally, the use of analgesics after the procedure will be measured and the incidence of flare-ups will be evaluated. Two study groups will be formed to undergo multiple-visit endodontic treatment. The intervention group will receive intracanal medication of calcium hydroxide, while the control group will have the root canal left empty between appointments.
CONDITIONS
Official Title
Multiple-Visit RCT in Teeth With SAP: Interappointment Dressing or Not?
Who Can Participate
Eligibility Criteria
You may qualify if you...
- ASA grade I or II
- Age 18 years or older
- Permanent teeth only
- Pulp diagnosis of necrosis or previously treated
- Diagnosed with symptomatic apical periodontitis
- Teeth sensitive to percussion or palpation
- Initial periapical index (PAI) score between 3 and 5
- Signed consent to participate in clinical research
You will not qualify if you...
- Does not meet all inclusion criteria
- Pregnant women
- Use of corticosteroids or antibiotics within the last 3 months
- Pain in an area different from the tooth being treated
- Teeth that cannot be isolated with a rubber dam
- Teeth with extensive decay that cannot be restored
- Teeth with root canal abnormalities such as internal resorption or perforation
- Teeth with incomplete root formation
- Fractured teeth with periodontal disease
- Teeth with periodontal pockets 4 mm or deeper or bone loss at root bifurcation
- Teeth with periodontal attachment loss of 5 mm or more
- Teeth with pus present at the time of root canal filling
- Teeth showing under- or over-extension of root canal filling beyond specified limits
- Teeth without permanent restoration within one month after root canal treatment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
School of Dentitry, Aristotle University of Thessaloniki
Thessaloniki, Central Macedonia, Greece, 54124
Actively Recruiting
Research Team
K
Konstantinos Kodonas, Ass.Prof.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here