Actively Recruiting
Multiprofen-CC to Reduce Pain in Hand Arthritis
Led by St. Joseph's Healthcare Hamilton · Updated on 2026-05-04
42
Participants Needed
1
Research Sites
72 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This clinical trial aims to find out if using 1 gram of Multiprofen-CC cream on the hands three times a day for 4 weeks can help reduce pain in adults with hand osteoarthritis, compared to a placebo (a cream with no active medicine). The research team will also look at how Multiprofen-CC affects hand function, opioid use, and how patients feel about their overall improvement. In addition, the research team will keep track of any side effects. Participants will: * Use both Multiprofen-CC and a placebo (a cream with no active medicine) during the study, in a random order. * Be asked to apply 1 gram of cream to their hands three times a day for 2 weeks, following the manufacturer's instructions. * Attend a visit before starting the study, after 2 weeks, and after 6 weeks. * Report any symptoms they experience during the study.
CONDITIONS
Official Title
Multiprofen-CC to Reduce Pain in Hand Arthritis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults 18 years or older
- Diagnosed with hand osteoarthritis according to American College of Rheumatology criteria
- Experience pain and/or loss of function in one or both hands that interferes with daily life
- Provide informed consent
You will not qualify if you...
- Unable to provide informed consent
- Unable or unwilling to follow the study protocol
- Known allergy or contraindication to study drugs or ingredients
- Have open wounds, cuts, or skin conditions on the hands
- Pregnant or breastfeeding
- History of impaired kidney or liver function
- Rheumatoid arthritis or other inflammatory arthropathy
- Hand surgery within the past 6 months or planned during the study period
- Use daily opioids (other than short-acting codeine) for chronic pain conditions other than hand arthritis
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
St. Joseph's Healthcare Hamilton
Hamilton, Ontario, Canada, L8N4A6
Actively Recruiting
Research Team
B
Breanne Flood, MSc
CONTACT
K
Kim Irish, BSW
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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