Actively Recruiting

Early Phase 1
Age: 21Years +
All Genders
ID05760885

Multisensory Augmentation to Improve Standing Balance in People With Chronic Stroke

Led by VA Office of Research and Development · Updated on 2026-01-06

36

Participants Needed

1

Research Sites

102 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Many people who have experienced a stroke struggle with balance problems, which may be partly caused by sensory issues. Researchers are evaluating whether sensory augmentation, a non-invasive method using vibration to enhance sensory information, can help improve balance in individuals with chronic stroke. This early phase 1 study aims to design a new multisensory augmentation approach that provides artificial feedback to the nervous system about body movement to prevent balance loss. Participants will take part in a 10-week balance training program consisting of 20 sessions where they stand on a platform that moves under their feet. Half of the participants will receive sensory augmentation during training, with vibration intensity controlled by their center of pressure motion, while the other half will undergo the same balance training without sensory stimulation. The difficulty of the training tasks will gradually increase over the sessions. During the study, researchers will assess balance improvements using clinical and biomechanical measures before and after the training period, focusing on changes in the Berg Balance Scale score. Participants must be able to stand independently for at least one minute and will be monitored for safety. The study will help determine if multisensory augmentation leads to sustained improvements in standing balance after stroke.

CONDITIONS

Official Title

Multisensory Augmentation for Post-stroke Standing Balance

Who Can Participate

Age: 21Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age of at least 21 years
  • Stroke experienced at least 6 months before participation
  • Berg Balance Scale score less than 52
  • Ability to stand independently for at least 1 minute without wearing an AFO or other brace that would prevent stimulation to the ankle or foot sole
  • Provision of informed consent
Not Eligible

You will not qualify if you...

  • Resting blood pressure higher than 220/110 mm Hg
  • History of unstable cardiac arrhythmias, hypertrophic cardiomyopathy, severe aortic stenosis, angina, or dyspnea at rest or during daily activities
  • Pre-existing neurological disorders or dementia
  • Severe visual impairment
  • History of deep vein thrombosis or pulmonary embolism within 6 months
  • Uncontrolled diabetes with recent weight loss, diabetic coma, or frequent insulin reactions

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Ralph H. Johnson VA Medical Center, Charleston, SC

Charleston, South Carolina, United States, 29401-5703

Actively Recruiting

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Research Team

J

Jesse C Dean, PhD

A

Aaron E Embry, DPT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

Frequently Asked Questions

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