Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT06363981

Multisite rTMS for Mood, Cognitive Impairment and Other Symptoms of Depression

Led by Jakub Antczak · Updated on 2024-10-15

90

Participants Needed

1

Research Sites

149 weeks

Total Duration

On this page

Sponsors

J

Jakub Antczak

Lead Sponsor

A

Andrzej Frycz Modrzewski Krakow University

Collaborating Sponsor

AI-Summary

What this Trial Is About

Depressed mood is the main symptom of depression, but other symptoms like cognitive impairment, anhedonia or sleep disorders may also contribute to patients suffering and are difficult to treat. rTMS is a relatively novel treatment option, whose therapeutic potential is still investigated and optimized. The aim of this study is to assess the effect of rTMS applied over two stimulation sites on cognitive impairment, anhedonia and sleep disorders in depression.

CONDITIONS

Official Title

Multisite rTMS for Mood, Cognitive Impairment and Other Symptoms of Depression

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with moderate or severe depressive episode without psychotic symptoms according to ICD-10
  • Hamilton Depression Rating Scale score between 20 and 35 at inclusion
  • Athens Insomnia Scale score of 8 or more
  • Score of 3 or more on items 4 and 21 of the Beck Depression Inventory 2
  • Experiencing memory and concentration problems related to the onset of depression
Not Eligible

You will not qualify if you...

  • Contraindications to transcranial magnetic stimulation such as having ferromagnetic elements in the head, pregnancy, or epilepsy
  • Presence of psychotic symptoms at the time of inclusion
  • Suicidal thoughts or attempts within three months before inclusion

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The Education of Research and Development Center, Babinski Clinical Hospital

Krakow, Poland, 30393

Actively Recruiting

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Research Team

W

Wojciech Korzeniowski, MD

CONTACT

J

Jakub Antczak, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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Multisite rTMS for Mood, Cognitive Impairment and Other Symptoms of Depression | DecenTrialz