Actively Recruiting
Multisite Transcranial Direct Current Stimulation to Promote Hand Function Recovery After Stroke
Led by Chinese University of Hong Kong · Updated on 2024-09-03
50
Participants Needed
1
Research Sites
172 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
A novel multisite high definition tDCS (HD-tDCS) in healthy people showed that such network-targeted stimulation could enhance motor excitability beyond traditional stimulation which targeting only one region. It showed that the excitability following multisite HD-tDCS was more than double the increase following conventional tDCS. To consider the various lesion site of different stroke survivors. The electrode placements based on personalized lesion profiles and anatomical features can be determined using finite element modeling, with lesion profiles generated from fMRI and advanced algorithms calculating the current density to maximize the modulation effect. Combining motor network interaction and the new multisite electrode montage may further provide a potential to facilitate stroke recovery.
CONDITIONS
Official Title
Multisite Transcranial Direct Current Stimulation to Promote Hand Function Recovery After Stroke
Who Can Participate
Eligibility Criteria
You may qualify if you...
- First-ever stroke with stroke duration longer than 12 months
- Mild to moderate upper extremity motor deficit with Fugl-Meyer Assessment scores between 15 and 53
- Detectable voluntary muscle signals from specific hand muscles (flexor digitorum and extensor digitorum)
- Modified Ashworth Score below 3 for these hand muscles
- Mini Mental State Examination score above 21 indicating sufficient cognitive function
You will not qualify if you...
- History of epilepsy or other conditions that prevent brain stimulation
- Severe joint contracture or pain caused by neurological, neuromuscular, or orthopedic diseases
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Department of Biomedical Engineering, The Chinese University of Hong Kong
Hong Kong, Hong Kong
Actively Recruiting
Research Team
R
Raymond Kai-yu Tong, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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