Actively Recruiting
Muscle Connective Tissue in Limb Development and Disease
Led by King's College London · Updated on 2025-08-27
150
Participants Needed
5
Research Sites
1066 weeks
Total Duration
On this page
Sponsors
K
King's College London
Lead Sponsor
G
Great Ormond Street Hospital for Children NHS Foundation Trust
Collaborating Sponsor
AI-Summary
What this Trial Is About
The objective of this work is to understand how the disruption of the muscle connective tissue contributes to the limb soft-tissue defects in radial dysplasia. In parallel, the researchers will investigate the role of muscle connective tissue in normal limb development.
CONDITIONS
Official Title
Muscle Connective Tissue in Limb Development and Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with a clinical diagnosis of radial dysplasia, requiring reconstructive surgery
- Either sex
- Informed (parental) consent to participate
- Patients with an injury requiring reconstructive surgery
- Either sex
- Informed (parental) consent to participate
You will not qualify if you...
- Patients with a clinical diagnosis of radial dysplasia, but not requiring reconstructive surgery
- Patients with a diagnosis other than radial dysplasia
- Patients with extensive previous scarring to their forearm and hand
- Patients with a significant pathological skin or soft tissue lesion at the donor site
- Patients with extensive previous scarring to their forearm and hand
- Patients with a significant pathological skin or soft tissue lesion at the donor site
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 5 locations
1
Oxford University Hospitals
Oxford, Oxfordshire, United Kingdom, OX3 9DU
Actively Recruiting
2
Royal Free Hospital
London, United Kingdom, NW3 2QG
Actively Recruiting
3
Guy's and St Thomas' Hospital
London, United Kingdom, SE1 7EH
Actively Recruiting
4
Chelsea and Westminster Hospital NHS Foundation Trust
London, United Kingdom, SW10 9NH
Actively Recruiting
5
Great Ormond Street Hospital for Children NHS Foundation Trust
London, United Kingdom, WC1N 3JH
Actively Recruiting
Research Team
M
Malcolm Logan, BSc PhD
CONTACT
G
George Murphy, PhD FRCS
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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