Actively Recruiting
Muscle Health Measurements Using Electrical Impedance Myography
Led by Beth Israel Deaconess Medical Center · Updated on 2026-04-03
150
Participants Needed
1
Research Sites
125 weeks
Total Duration
On this page
Sponsors
B
Beth Israel Deaconess Medical Center
Lead Sponsor
N
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study is being done to further develop a device, the mScan, to measure muscle health as compared to measurements of muscle health using MRI (magnetic resonance imaging). This device is held against the skin and uses Electrical Impedance Myography (EIM). EIM uses a very small, noninvasive (e.g. no needles), brief (about 6 seconds), and painless electrical current to measure the muscle. The investigators will look at how the mScan predicts the muscle measurements seen on MRI in people with and without muscle disease. The investigators hope that this can be used in the future as a quick, convenient and less time-consuming way than MRI to assess muscle health. This could be used to measure how well treatments for different muscle disorders are working over a period of time.
CONDITIONS
Official Title
Muscle Health Measurements Using Electrical Impedance Myography
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ages 18 to 89 years
- Evidence of a primary myopathic condition confirmed by chart review, genetic testing, serology, or previous muscle biopsy
You will not qualify if you...
- Unable to lie flat or history of claustrophobia
- More than 1+ lower extremity edema
- Multiple other muscle pathologies affecting lower extremity muscles to be studied
- Pregnancy
- Contraindications for MRI such as incompatible pacemaker, deep brain stimulator, or lower extremity hardware
- Contraindications to DXA Scan including recent radioisotope studies (within 15 days), recent radiographic contrast imaging (within 7 days), weight over 450 lbs, or recent calcium supplements/antacids (within 24 hours)
- Severe obesity with BMI over 35 kg/m2
- Chronic skin conditions with ulcerations interfering with EIM electrode contact or causing discomfort
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Beth Israel Deaconess Medical Center
Boston, Massachusetts, United States, 02215
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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