Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05706831

Music Intervention and Transcranial Electrical Stimulation for Neurological Diseases

Led by Istituti Clinici Scientifici Maugeri SpA · Updated on 2025-06-04

90

Participants Needed

1

Research Sites

226 weeks

Total Duration

On this page

Sponsors

I

Istituti Clinici Scientifici Maugeri SpA

Lead Sponsor

U

University of Bari Aldo Moro

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to evaluate the efficacy of a musical interventionand non-invasive brain stimulation in neurological patients. The main questions it aims to answer are: * to evaluate the residual neuroplastic processes in DOC state related to music exposure * to determine the putative modulation of the aforementioned processes and the clinical outcome of DOC patients by non-pharmacological strategies, i.e., electric (tDCS) and music stimulation * to evaluate the impact of this intervention on caregiver's burden and psychological distress. Participants will be randomly assigned to one of three different music-listening intervention groups. Primary outcomes will be clinical, that is based on the neurologist's observations of clinical improvement, and neurophysiological, collected pre-intervention, post-intervention and post-placebo.

CONDITIONS

Official Title

Music Intervention and Transcranial Electrical Stimulation for Neurological Diseases

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age > 18 years
  • Post-stroke aphasia
  • Post-stroke neglect
  • Patients with disorders of consciusness (DOC)
Not Eligible

You will not qualify if you...

  • No auditory injury
  • No history of neurological disease
  • No history of psychiatric disease
  • Previous stroke
  • Use of alcohol and drugs
  • Premorbid dementia

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Istituti Clinici Scientifici Maugeri

Bari, Ba, Italy, 70025

Actively Recruiting

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Research Team

S

Simona Spaccavento

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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Music Intervention and Transcranial Electrical Stimulation for Neurological Diseases | DecenTrialz