Actively Recruiting

Age: 5Years - 14Years
All Genders
NCT06545708

Music Perception in SeLECTs

Led by Hospices Civils de Lyon · Updated on 2024-12-09

100

Participants Needed

2

Research Sites

102 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Self-limited epilepsy with centrotemporal spikes (SeLECTS) is the most frequent epilepsy syndrome in children between the ages of 4 and 13 years. SeLECTS is associated in 15 to 30% of patients with specific cognitive deficits, including in particular disorders in language, visuo-spatial memory, declarative memory, and attention. SeLECTS has the potential to evolve into Landau-Kleffner syndrome, the most extreme form of SeLECTS including symptoms of auditory agnosia and aphasia, with potential risks of persistent neuropsychological impairments. In a recent study in adults who had suffered Landau-Kleffner syndrome during childhood, the investigators have shown that these patients, in addition to their known deficit in verbal short-term memory, also exhibit persistent musical difficulties during adulthood, with in particular deficit in melody and rhythm short-term memory. In the present project, the investigators intend to enlarge the understanding of cognitive deficits generated by SeLECTS in children by investigating the integrity of music perception, both for melody and rhythm. To date, data about music perception in children with epilepsy are scarce and we do not know how distinct components of melody and rhythm perception and memory may be altered.

CONDITIONS

Official Title

Music Perception in SeLECTs

Who Can Participate

Age: 5Years - 14Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Subject aged between 5 and 14 years old
  • Parents or guardians do not oppose the child's participation
  • No major cognitive impairment and able to understand and follow instructions
  • Affiliated to a social security scheme
  • Motivated to participate in the project
  • Proficient in French language
  • For control group: no neurological or psychiatric history
  • For seizure disorder group: no neurological (except SeLECTS) or psychiatric history
  • Diagnosis of self-limited epilepsy with centro-temporal spikes by a qualified healthcare professional
Not Eligible

You will not qualify if you...

  • Major cognitive impairment or inability to understand and follow instructions
  • Refusal to participate in the study
  • Pregnant or breastfeeding minors

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 2 locations

1

Centre Hospitalier Le Vinatier (Bât. 452),

Bron, Bron, France, 69500

Not Yet Recruiting

2

Hospices Civils de Lyon

Bron, Bron, France, 69500

Actively Recruiting

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Research Team

M

Maria PAPADOPOULOU, MD

CONTACT

A

Anne CACLIN, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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