Actively Recruiting

Phase Not Applicable
Age: 18Years - 89Years
All Genders
NCT05151562

Music Therapy for Patients With Alzheimer's Disease

Led by Johns Hopkins University · Updated on 2026-05-06

60

Participants Needed

1

Research Sites

310 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study is designed to assess the feasibility that individualized reminiscence-based virtual music therapy sessions can enhance autobiographical memory, mood, and cognition in patients with mild cognitive impairment (MCI) or mild dementia due to Alzheimer's Disease (AD). 60 patients with MCI or mild dementia due to AD will receive two 30 minutes reminiscence-targeted virtual music therapy interventions per week for 8 weeks (a total of 16 sessions). Participants' (or supported by the study partner) self-reported and measurable outcomes including cognitive, anxiety, quality of life, and autobiographical memory will be assessed before and after the 8-week course of treatment. Blood-oxygenation level-dependent (BOLD) in functional magnetic resonance imaging (fMRI) will also be also measured before and after the 8-week course of treatment.

CONDITIONS

Official Title

Music Therapy for Patients With Alzheimer's Disease

Who Can Participate

Age: 18Years - 89Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 to 89 years
  • Diagnosis of mild cognitive impairment with MoCA score 18-25 or early Alzheimer's Disease with MoCA score 17-24
Not Eligible

You will not qualify if you...

  • History of head trauma, traumatic brain injury, or concussion with loss of consciousness longer than 2 minutes
  • Claustrophobia that prevents MRI scanning
  • Medical devices incompatible with MRI, such as cardiac pacemaker, implanted defibrillator, brain aneurysm clip, or inner ear implant
  • Prior history as a metal worker or presence of certain metallic objects in the body
  • Exclusion based on MRI screening form assessments

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Johns Hopkins School of Medicine

Baltimore, Maryland, United States, 21205

Actively Recruiting

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Research Team

A

Alexander Pantelyat, MD

CONTACT

K

Kyurim Kang, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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