Actively Recruiting

Age: 18Years +
All Genders
NCT06917066

MYLEAD Spanish Prospective Registry

Led by Hospital Clínico Universitario de Valladolid · Updated on 2025-04-08

500

Participants Needed

1

Research Sites

109 weeks

Total Duration

On this page

Sponsors

H

Hospital Clínico Universitario de Valladolid

Lead Sponsor

M

Meril Life Sciences Pvt. Ltd.

Collaborating Sponsor

AI-Summary

What this Trial Is About

Investigator-initiated, prospective, multicentre registry, whose objectives are: 1/ to evaluate the incidence of conduction defects and the need of pacemaker implantation post-procedure, at discharge, at 30 days and at 1 year post Myval transcatheter heart valve deployment, and 2/ To evaluate the factors determining in-hospital and late (at 30 days and 1 year) conduction defects post Myval transcatheter heart valve. Patients with Severe Aortic stenosis undergoing TAVR using Myval Transcatheter Heart Valve that meet all inclusion criteria and any exclusion criteria will be able to participate in this study if they sign the informed consent. Electrocardiogram, echocardiogram and computed tomography will be performed to patients at different time points (Baseline, post-procedure, discharge, 30 days and 1 year post procedure) and their parameters will be added into a dedicated REDCAP database.

CONDITIONS

Official Title

MYLEAD Spanish Prospective Registry

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients (over 18 years of age)
  • Patients with Severe Aortic stenosis undergoing TAVR using Myval Transcatheter Heart Valve.
Not Eligible

You will not qualify if you...

  • Patients with pre-existing permanent pacemaker.
  • Patients unable or unwilling to follow up for pre and post procedure clinical assessments and investigations.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hospital Clínico Universitario de Valladolid

Valladolid, Valladolid, Spain, 47003

Actively Recruiting

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Research Team

I

Ignacio J Amat-Santos, PhD

CONTACT

C

Carlos Baladrón, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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MYLEAD Spanish Prospective Registry | DecenTrialz