Actively Recruiting
Oral Health Intervention for Patients with Heart Attack and Gum Disease: A Randomized Study to Assess Periodontal Treatment Effects
Led by Shanghai 10th People's Hospital · Updated on 2024-12-20
100
Participants Needed
1
Research Sites
265 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying patients who have acute myocardial infarction (heart attack) and also suffer from periodontal disease (gum disease). The goal is to create a shared database of these patients and understand the benefits of treating periodontal disease on heart attack outcomes through a simulated randomized controlled trial. This study aims to promote the use of oral health treatments in clinical care for these patients. Patients in the intervention group receive a detailed dental examination by specialists. All permanent teeth, except third molars, are checked for plaque, gum bleeding, and attachment loss using dental tools. Treatment includes education about gum disease, removal of plaque and tartar, fixing decayed teeth, and cleaning procedures. No preventative antibiotics are used before the treatment. Participants will be monitored for changes in heart function, specifically ejection fraction, from enrollment until six months after treatment. The study collects detailed dental and medical data to evaluate the impact of periodontal care on heart health. Patients provide informed consent and are followed closely to assess both oral and cardiac outcomes over the study period.
CONDITIONS
Official Title
Myocardial Infarction and Periodontitis: Periodontal Health Intervention.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients diagnosed with ST-segment elevation myocardial infarction (STEMI)
- Severe periodontal disease with at least 5 teeth showing clinical attachment loss of 4 mm or more
- Subgingival probing depth of 6 mm or more
- At least 8 teeth with gingival bleeding on probing
- Age 30 years or older
- Provided written informed consent
You will not qualify if you...
- Under 30 years old
- HIV positive, chronic inflammation, tumor disease, drug dependence
- Use of anticonvulsants or immunosuppressive agents
- Pregnancy or lactation
- Significant tooth loss with fewer than 8 remaining teeth
- Long hospital stay over 10 days
- New myocardial infarction before randomization
- Presence of stent thrombosis
- Refusal to sign informed consent
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Shanghai Tenth People's Hospital
Shanghai, Shanghai Municipality, China, 200092
Actively Recruiting
Research Team
J
Jiawen Wu
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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