Actively Recruiting

Phase Not Applicable
Age: 30Years +
All Genders
ID06745141

Oral Health Intervention for Patients with Heart Attack and Gum Disease: A Randomized Study to Assess Periodontal Treatment Effects

Led by Shanghai 10th People's Hospital · Updated on 2024-12-20

100

Participants Needed

1

Research Sites

265 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying patients who have acute myocardial infarction (heart attack) and also suffer from periodontal disease (gum disease). The goal is to create a shared database of these patients and understand the benefits of treating periodontal disease on heart attack outcomes through a simulated randomized controlled trial. This study aims to promote the use of oral health treatments in clinical care for these patients. Patients in the intervention group receive a detailed dental examination by specialists. All permanent teeth, except third molars, are checked for plaque, gum bleeding, and attachment loss using dental tools. Treatment includes education about gum disease, removal of plaque and tartar, fixing decayed teeth, and cleaning procedures. No preventative antibiotics are used before the treatment. Participants will be monitored for changes in heart function, specifically ejection fraction, from enrollment until six months after treatment. The study collects detailed dental and medical data to evaluate the impact of periodontal care on heart health. Patients provide informed consent and are followed closely to assess both oral and cardiac outcomes over the study period.

CONDITIONS

Official Title

Myocardial Infarction and Periodontitis: Periodontal Health Intervention.

Who Can Participate

Age: 30Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients diagnosed with ST-segment elevation myocardial infarction (STEMI)
  • Severe periodontal disease with at least 5 teeth showing clinical attachment loss of 4 mm or more
  • Subgingival probing depth of 6 mm or more
  • At least 8 teeth with gingival bleeding on probing
  • Age 30 years or older
  • Provided written informed consent
Not Eligible

You will not qualify if you...

  • Under 30 years old
  • HIV positive, chronic inflammation, tumor disease, drug dependence
  • Use of anticonvulsants or immunosuppressive agents
  • Pregnancy or lactation
  • Significant tooth loss with fewer than 8 remaining teeth
  • Long hospital stay over 10 days
  • New myocardial infarction before randomization
  • Presence of stent thrombosis
  • Refusal to sign informed consent

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Shanghai Tenth People's Hospital

Shanghai, Shanghai Municipality, China, 200092

Actively Recruiting

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Research Team

J

Jiawen Wu

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

Frequently Asked Questions

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