Actively Recruiting
Myopia Control: a Comparison Study Between Atropine and MiSight
Led by Ann & Robert H Lurie Children's Hospital of Chicago · Updated on 2024-11-19
348
Participants Needed
1
Research Sites
149 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research project aims to provide additional knowledge of pharmacological and optical methods of myopia control and to gain a better understanding of the biometry of the pediatric eye, which contributes to the onset and progression of myopia. As a result, this study will improving our best practices for myopia control in pediatric patients.
CONDITIONS
Official Title
Myopia Control: a Comparison Study Between Atropine and MiSight
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Children aged 5 to 12 years at baseline exam
- Spherical equivalent refractive error from +0.50D (minimal farsightedness) to -7.50D (high myopia)
- Gestational age of 32 weeks or more
- Birth weight greater than 1500 grams
You will not qualify if you...
- Current or previous use of any myopia control treatment
- Use of bifocal, progressive-addition, or multifocal contact lenses currently or previously
- Known allergy to atropine or intolerance to contact lenses (allergy to one allows enrollment in other group)
- Abnormalities in cornea, lens, central retina, iris, or ciliary body
- History of strabismus, amblyopia, or nystagmus
- Previous treatment with atropine, pirenzepine, or other anti-muscarinic agents
- Use of orthoK, rigid gas permeable, or other myopia-reducing contact lenses
- Prior eyelid, strabismus, intraocular, or refractive surgery
- Down syndrome or cerebral palsy
- Diseases affecting eye accommodation, vergence, or movement (e.g., multiple sclerosis, Grave's disease, myasthenia gravis, diabetes mellitus, Parkinson's disease)
- Existing ocular or systemic/neurodevelopmental conditions influencing refractive development
- Any condition potentially influencing refractive development as judged by investigator
- Conditions affecting long-term eye health or requiring medications that may interact adversely with study treatments
- Inability to understand or perform study-related clinical tests
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Ann & Robert H. Lurie Children's Hospital of Chicago
Chicago, Illinois, United States, 60611
Actively Recruiting
Research Team
C
Chia-Ching Wu, MS
CONTACT
H
Hanta Ralay Ranaivo, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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