Actively Recruiting
Myosteatosis in Oeso-gastric Cancer: Clinical Impacts
Led by Cliniques universitaires Saint-Luc- Université Catholique de Louvain · Updated on 2024-05-17
50
Participants Needed
1
Research Sites
108 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of this project is to study the presence of cancer-associated adipocytes in oesogastric cancers and their possible links with myosteatosis. This research project has a retrospective component, the aim of which is to analyse the body component based on imaging in patients with oesogastric neoplasia in order to determine the incidence of myosteatosis and to study the relationship with oncological and prognostic data. The second part of the project is prospective and will collect biological material (skeletal muscle, adipose tissue, tumour, blood) for histological, molecular and genomic analyses and will analyse muscle function in patients with oesogastric cancer. It will address the role of adipocytes in the tumour microenvironment of oesogastric cancer, focusing on their interactions with the observed muscle myosteatosis and prognosis. In the future, it will help to identify signalling pathways, targets and patients who could benefit from appropriate treatment.
CONDITIONS
Official Title
Myosteatosis in Oeso-gastric Cancer: Clinical Impacts
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with cancer of the oesophagus, oeso-gastric junction or stomach
- Treatment and estimated survival of more than 3 months
- Signed informed consent
- Older than 18 years of age
You will not qualify if you...
- Neuromuscular or orthopedic pathology
- Cognitive disorders
- Psychiatric disorders
- Inability to communicate in French or English
AI-Screening
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Trial Site Locations
Total: 1 location
1
Cliniques universitaires Saint-Luc
Brussels, Belgium, 1200
Actively Recruiting
Research Team
Y
Yannick Deswysen, MD
CONTACT
N
Nicolas Lanthier, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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