Actively Recruiting
NAC vs Placebo on Opioid Use for Hysterectomy
Led by Medical University of South Carolina · Updated on 2025-10-14
240
Participants Needed
1
Research Sites
157 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study will enroll females who are ages 18 and older undergoing a laparoscopic or robotic, partial or full hysterectomy. Participants will be randomized to receive IV n-acetylcysteine or placebo during the first 60 minutes of their procedure. At various time points after the procedure patients will be asked to report their pain scores, and any pain medication taken.
CONDITIONS
Official Title
NAC vs Placebo on Opioid Use for Hysterectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Undergoing elective laparoscopic or robotic, full, or partial hysterectomy procedure
- 18 years of age and older
You will not qualify if you...
- Less than 40kg in weight
- Unable to provide written, informed consent
- History of an adverse or anaphylactoid reaction to acetylcysteine
- Active asthma, wheezing, or using inhaled bronchodilators
- Non-English speaking
- Insulin dependent diabetes if D5W is required
- Blood clotting disorders
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Medical University of South Carolina
Charleston, South Carolina, United States, 29425
Actively Recruiting
Research Team
H
Haley Nitchie, MHA
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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