Actively Recruiting
Nafamostat Efficacy in Phase 3 Registrational CRRT Study
Led by Talphera, Inc · Updated on 2025-10-15
70
Participants Needed
10
Research Sites
67 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
A prospective, randomized, placebo-controlled clinical study to investigate the safety and efficacy of Niyad (nafamostat mesylate) for anticoagulation of extracorporeal blood circulating through a dialysis filter in patients undergoing CRRT who cannot tolerate heparin or are at higher risk for bleeding.
CONDITIONS
Official Title
Nafamostat Efficacy in Phase 3 Registrational CRRT Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients requiring CRRT or undergoing CRRT initiated within the prior 48 hours
- Patients who cannot tolerate heparin or are at high risk of bleeding
You will not qualify if you...
- Patients weighing less than 50 kg
- Patients receiving systemic anticoagulation
- Patients with active bleeding
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 10 locations
1
University of California Los Angeles
Los Angeles, California, United States, 90095
Actively Recruiting
2
AdventHealth
Orlando, Florida, United States, 32804
Not Yet Recruiting
3
Henry Ford Health
Detroit, Michigan, United States, 48202
Actively Recruiting
4
University of New Mexico
Albuquerque, New Mexico, United States, 87131
Actively Recruiting
5
Northwell Health
Great Neck, New York, United States, 11021
Actively Recruiting
6
Mount Sinai
New York, New York, United States, 10029
Actively Recruiting
7
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States, 45229
Actively Recruiting
8
University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, United States, 15213
Actively Recruiting
9
Medical University of South Carolina
Charleston, South Carolina, United States, 29425
Actively Recruiting
10
Baylor University Medical Center
Dallas, Texas, United States, 75246
Actively Recruiting
Research Team
N
Nazneen Patel
CONTACT
C
Chris Houchins
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here