Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT06671886

NAFLD Clinical Care Pathway

Led by VA Office of Research and Development · Updated on 2025-11-14

32

Participants Needed

1

Research Sites

249 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Non-alcoholic fatty liver disease (NAFLD) is a new condition that has become the most common chronic liver disease in the world and a main cause of liver cirrhosis, liver failure and liver cancer. Obesity and diabetes, conditions that are very common among Veterans are the main risk factors for NAFLD. Therefore, the burden of NAFLD and its complications among Veterans is substantial. However, most VA patients with NAFLD are undiagnosed and untreated, and their care is not consistent with practice guidelines. The NAFLD Clinical Care Pathway (NCCP) intervention seeks to close this major gap in the care of Veterans by automatically identifying patients at risk of NAFLD, calculating their risk scores of having severe NAFLD, and educating the primary care providers on the diagnosis and treatment of NAFLD. This clinical trial will test the benefit of this NCCP intervention against usual care in increasing the rates of NAFLD diagnosis as well as referral to and enrollment in appropriate treatment. The study will also identify barriers and promotors of future NCCP implementation.

CONDITIONS

Official Title

NAFLD Clinical Care Pathway

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient Aligned Care Teams (PACT) at the Michael E. DeBakey VA Medical Center
Not Eligible

You will not qualify if you...

  • PACTs with unstable leadership (pending departure or vacancy) at time of randomization
  • PACTs that participated in focus groups during the first study aim to avoid cross contamination
  • PACTs that do not treat NAFLD
  • PACTs not located at the main hospital
  • PACTs with fewer than 100 visits within 3 months

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Michael E. DeBakey VA Medical Center, Houston, TX

Houston, Texas, United States, 77030-4211

Actively Recruiting

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Research Team

H

Hashem B El-Serag, MD MPH

CONTACT

K

Kyler Godwin, PhD MPH BS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

2

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