Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06494514

NALIRIFOX Combined With PD-1 Sequential Radiotherapy Versus AG Combined With PD-1 Sequential Radiotherapy as First-line Treatment of Locally Advanced Pancreatic Cancer

Led by Du Juan · Updated on 2024-07-10

40

Participants Needed

2

Research Sites

156 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of the study is to evaluate the efficacy and safety of NALIRINOX combined with PD-1 synchronous sequential SBRT or AG combined with PD-1 synchronous sequential SBRT as first line systematical therapy in patients with ocally advanced pancreatic cancer.

CONDITIONS

Official Title

NALIRIFOX Combined With PD-1 Sequential Radiotherapy Versus AG Combined With PD-1 Sequential Radiotherapy as First-line Treatment of Locally Advanced Pancreatic Cancer

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Histologically or cytologically confirmed pancreatic cancer
  • ECOG performance status of 0 to 2
  • Radiographically diagnosed locally advanced pancreatic cancer per NCCN guidelines
  • No prior anti-tumor therapy
  • Able and willing to provide written informed consent
Not Eligible

You will not qualify if you...

  • Prior anti-tumor therapy of any kind
  • Severe infection greater than NCI CTC grade 2
  • Autoimmune disease or immune deficiency treated with immunosuppressive drugs
  • Bleeding tendency
  • Pregnant or breastfeeding women

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

FirstNanjingMU

Nanjing, Jiangsu, China, 025

Not Yet Recruiting

2

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Nanjing, Jiangsu, China, 025

Actively Recruiting

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Research Team

J

Juan Du, M.D. Ph.D

CONTACT

J

Juan Du

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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