Actively Recruiting
Nanochon Chondrograft First in Human (FIH) Early Feasibility Study (EFS) - Canada
Led by Nanochon, Inc. · Updated on 2026-04-22
10
Participants Needed
2
Research Sites
69 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this First in Human study is to learn if the Nanochon Chondrograft Implant is a safe primary surgical treatment for participants with cartilage lesions in the knee. This study will include males and females between the ages of 22 and 60.
CONDITIONS
Official Title
Nanochon Chondrograft First in Human (FIH) Early Feasibility Study (EFS) - Canada
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female aged 22 to 60 years
- MRI knee evaluation completed within 6 months prior to enrollment
- Able to read and speak English
- Voluntarily signed informed consent form
You will not qualify if you...
- Known systemic cartilage or bone disorders such as osteoporosis, chondrodysplasia, or osteogenesis imperfecta
- Requires bilateral knee surgery
- Pregnant, planning pregnancy, or breastfeeding
- Significant illness reducing survival probability to 12 months (e.g., metastatic cancer)
- Known insulin dependent diabetes mellitus
- Steroid treatment (oral or IV) within past 6 months
- Receiving workman's compensation
- Receiving prescription narcotic medication
- Involved in litigation related to musculoskeletal injuries or disorders
- Prisoner or pending incarceration
- Comorbidities affecting participation or results (e.g., autoimmune disorders, HIV, neuropathic pain, fibromyalgia, restless leg syndrome, active infection, chronic pain management)
- Significant psychiatric disorders (major depression, anxiety disorders, bipolar disorder, schizophrenia)
- Substance or alcohol dependence or abuse
- Participating in another drug or device study that may interfere
- Claustrophobia or implanted metallic devices contraindicating MRI
- Known allergy or hypersensitivity to investigational device materials
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Fraser Orthopaedic Institute
New Westminster, British Columbia, Canada, V3L OE4
Actively Recruiting
2
University of British Columbia
Vancouver, British Columbia, Canada, V6T 1Z4
Actively Recruiting
Research Team
C
Chief Clinical Officer
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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