Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05844384

Nanodropper Use in Primary Open-Angle Glaucoma Patients: A Non-Inferiority Trial

Led by 59th Medical Wing · Updated on 2023-05-06

30

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

Sponsors

5

59th Medical Wing

Lead Sponsor

N

Nanodropper, Inc.

Collaborating Sponsor

AI-Summary

What this Trial Is About

This randomized, single-masked, crossover, non-inferiority trial aims to evaluate the safety and efficacy of Nanodropper-mediated microdrops of ocular hypotensive topical treatments (experimental intervention) compared to standard drops of the same medication(s) (active comparator) in Wilford Hall Ambulatory Surgical Center (WHASC) primary open-angle glaucoma (POAG) and ocular hypertension (OHTN) patients.

CONDITIONS

Official Title

Nanodropper Use in Primary Open-Angle Glaucoma Patients: A Non-Inferiority Trial

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with primary open-angle glaucoma or ocular hypertension over 18 years old
  • Taking up to two intraocular pressure lowering medications
  • Stable eye condition without progression in pressure, optic disc, retinal nerve fiber layer, or visual field changes within the last year
Not Eligible

You will not qualify if you...

  • Glaucoma types other than primary open-angle glaucoma or ocular hypertension, or other retinal diseases
  • Eye disease progression in the past year, including increased pressure or visual changes
  • Using more than two intraocular pressure lowering medications
  • Eye surgeries or laser treatments except selective laser trabeculoplasty (SLT) done less than 6 months ago

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Wilford Hall Ambulatory Surgical Center

Lackland Air Force Base, Texas, United States, 78236

Actively Recruiting

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Research Team

J

Jose E Capo-Aponte, OD, PhD

CONTACT

J

Jennifer Steger, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

OTHER

Number of Arms

2

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Nanodropper Use in Primary Open-Angle Glaucoma Patients: A Non-Inferiority Trial | DecenTrialz