Comparing Nasal Steam Therapy and Routine Care for Upper Respiratory Symptoms After Thyroid Surgery with Intubation in Adults Aged 19 to 69
Led by Ilsan Cha hospital · Updated on 2025-04-02
66
Participants Needed
1
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Researchers are evaluating the effects of nasal steam therapy compared to routine management for upper respiratory symptoms that happen after endotracheal intubation in adults aged 19 to 69 years who had thyroid gland surgery under anesthesia. The study aims to confirm how well nasal steam therapy works by randomly assigning 66 patients to either a nasal steam therapy group or a routine management group. This is a practical trial where treatments are chosen based on each patients condition and recorded for comparison.
The nasal steam therapy group receives steam inhalation treatment every other day for a total of three sessions, targeting specific acupoints on the face. The routine management group receives usual clinical care, including drugs commonly used to manage upper respiratory symptoms, with treatment decisions made by doctors based on symptom severity and improvement. Treatment lasts for five days, and drug use may continue after the study period if decided by the clinician.
Participants will be monitored from enrollment through treatment and follow-up visits, with assessments including the Wisconsin Upper Respiratory Symptom Survey-24 WURSS-24 up to day 15. Researchers will also track the incidence and severity of cough and quality of life related to thyroid cancer symptoms. All treatments, symptom changes, and patient-reported outcomes will be recorded to understand the therapies impact and safety over the study period.
CONDITIONS
Brief Title
Nasal Steam Therapy for Post-extubation Respiratory Events
Research Team
J
Jee Young Lee, MD(KMD), PhD
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match. Sign up to get personalized trial recommendations delivered to your inbox.
Underwent thyroid gland surgical removal with endotracheal intubation
American Society of Anesthesiologists (ASA) status I or II
Developed upper respiratory symptoms after surgery
Voluntarily agreed to participate and signed informed consent
You will not qualify if you...
Diagnosed with symptomatic gastroesophageal reflux disease
Chronic cough lasting more than 3 months before surgery, including bronchial asthma and COPD
Developed other respiratory infections within the past month
Taking or needing medications that affect treatment interpretation
Scheduled for additional major treatments like reoperation, chemotherapy, or radiotherapy during the trial
Pregnant, breastfeeding, or planning pregnancy during the study
Expected difficulty complying with treatment, visits, or questionnaires as decided by medical staff
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Treatment
Duration - 5 days
Participants receive either nasal steam therapy every other day for a total of 3 sessions or routine management based on clinical judgment to improve upper respiratory symptoms after surgery.
3 visits for nasal steam therapy or visits as needed for routine management
Follow-up
Duration - 7 days
Participants are monitored for symptom improvement and quality of life after treatment completion.
1 follow-up visit on Day 15
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Similar Trials
Phase I Study of 177Lu-CTR-FAPI Radioligand Therapy for Thyroid Cancer Evaluating Safety and Effectiveness
Safety and Effectiveness of a New 18F Labeled Fibroblast Activation Protein Probe for Early Tumor Detection
Including Lung, Pancreatic, Neuroendocrine, and Thyroid Cancers
Phase III Study Comparing Preventive Central Neck Dissection Versus No Dissection in Adults with Low-risk Papillary Thyroid Cancer
Comparing Video and Direct Laryngoscopy for Intubating Newborn Babies
A Randomized Study to Improve First-Attempt Success and Safety
Phase 3 Trial of AL2846 Capsules Versus Placebo for Advanced or Metastatic Radioiodine-Refractory Differentiated Thyroid Cancer After VEGFR-Targeted Therapy
Phase 2 Study of Avutometinib and Defactinib for Treating RAF Dimer-Driven Radioiodine-Refractory Differentiated and Anaplastic Thyroid Cancer
Comparison of Meaning-Centered Psychotherapy and Cognitive Behavioral Therapy for Mexican Adults with Advanced Cancer
Collecting Information on Use of Redifferentiation Medications for Radioactive Iodine-Refractory Thyroid Cancer in Routine Care
Phase 1 Study of PF-07799544 Alone or with PF-07799933 in Adults With BRAF V600 Mutation Advanced Solid Tumors
Phase 1 Study of PF-07799933 Alone or With Other Medicines for Advanced Solid Tumors with BRAF Gene Changes in Participants 16 Years and Older
Have more questions? Get in touch with our team for quick support
Published Research Related To This Trial
Effectiveness and Safety of Nasal Herbal Steam Therapy for Post-Extubation Respiratory Symptoms: A Methodology of Pragmatic Randomized Controlled, Parallel Grouped Study.