Comparing Nasojejunal and Oral Feeding After Endoscopic Drainage of Walled Off Pancreatic Necrosis in Adults with Acute Pancreatitis

What this Trial Is About

Researchers are evaluating whether nasojejunal feeding is better than oral feeding in patients undergoing endoscopic drainage of walled off pancreatic necrosis after acute pancreatitis. This randomized control trial aims to assess differences in infection rates, feed tolerance, weight gain, and the need for re-intervention between the two feeding methods. The study is conducted with adult patients aged 18 to 75 years who have symptomatic walled off necrosis requiring drainage. Participants will be randomly assigned to receive either nasojejunal feeding or start oral feeding following an endoscopic ultrasonography guided cystogastrostomy procedure. The nasojejunal tube will be placed immediately after the drainage procedure for those in the experimental group, while the comparator group will begin oral feeding. This pilot study will monitor the effects of each feeding method over a period of 14 days. During the study, researchers will closely monitor nutritional failure as the primary outcome within 14 days. Secondary outcomes include the incidence of infections, new onset organ failure, re-intervention rates, weight changes, and inflammatory marker levels during the same timeframe. Participants will be followed for the full 14 days after their procedure to assess these measures and to ensure safety and proper monitoring throughout the study period.

Nasojejunal Feeding Versus Oral Feeding Following Endoscopic Drainage of Walled Off Pancreatic Necrosis