Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06966934

Nasopharyngeal Airway Combined With Nasal High-flow Oxygen Therapy During Painless Gastroscopy in Obesity Patients

Led by Nanjing First Hospital, Nanjing Medical University · Updated on 2025-07-22

364

Participants Needed

1

Research Sites

54 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Gastroscopy is a commonly used, direct, and reliable method for screening and diagnosing digestive tract diseases. However, as an invasive examination, it can cause adverse reactions such as pain, nausea, vomiting, and choking cough in patients. Compared with ordinary gastroscopy, painless gastroscopy offers higher comfort and satisfaction for patients and greater convenience for endoscopists during operation. The most common complication of painless gastroscopy diagnosis and treatment is hypoxia. High-flow nasal cannulala (HFNC) provides a higher oxygen concentration and flow rate than an ordinary nasal catheter. It has the functions of heating and humidifying, which can relieve the pressure on the nasal mucosa cilia, keep the airway unobstructed and moist, and reduce the risk of epistaxis. Due to changes in airway anatomical structures such as fat accumulation in the head and neck and hyperplasia of oropharyngeal soft tissues, obese patients are more prone to hypoxia during gastroscopy under sedation. Therefore, HFNC is often used to reduce the occurrence of hypoxia. The nasopharyngeal airway (NPA) is used to maintain the patency of the upper respiratory tract and is suitable for patients with spontaneous breathing but partial obstruction of the upper respiratory tract. It is worth exploring how effective the combination of HFNC and NPA is in improving hypoxemia in obese patients during sedation.

CONDITIONS

Official Title

Nasopharyngeal Airway Combined With Nasal High-flow Oxygen Therapy During Painless Gastroscopy in Obesity Patients

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients undergoing painless gastroscopy
  • Age greater than 18 years old
  • American Society of Anesthesiologists (ASA) physical status classification from Grade I to Grade III
  • Body Mass Index (BMI) greater than 28 kg/m�b2
Not Eligible

You will not qualify if you...

  • Contraindications to endoscopic procedures or refusal of sedation/anesthesia
  • Allergy to propofol, eggs, soybeans, or milk
  • Gastrointestinal obstruction or gastric emptying disorders
  • Acute pharyngitis, tonsillitis, or upper respiratory tract infections
  • Acute worsening of respiratory diseases such as asthma, bronchitis, or COPD
  • Acute arrhythmia or severe heart diseases including congenital or valvular diseases
  • Severe liver or kidney failure requiring alternative treatment
  • Severe mental disorders requiring medication
  • Moderate or severe anemia, abnormal blood clotting, or blood diseases
  • Nasal cavity lesions causing severe congestion
  • Pregnant or breastfeeding individuals

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Nanjing First Hospital

Nanjing, China

Actively Recruiting

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Research Team

J

Jing Hu, Master

CONTACT

T

Tao Shan, Master

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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