Using Nasopharyngeal Airway and Nasal High-flow Oxygen Therapy During Painless Gastroscopy in Adults with Obesity

What this Trial Is About

Researchers are evaluating the use of a nasopharyngeal airway NPA combined with nasal high-flow oxygen therapy HFNC during painless gastroscopy in patients with obesity. Gastroscopy is a common method to screen and diagnose digestive tract diseases but can cause discomfort and adverse reactions. Obese patients face a higher risk of hypoxia during sedation due to changes in airway anatomy and respiratory function, so this study aims to see if combining NPA with HFNC can reduce hypoxia incidents in this group. The study compares two approaches during painless gastroscopy for obese patients. One group receives high-flow nasal cannula oxygen at 30 Lmin after sedation, while the other group receives the same oxygen flow plus the insertion of an NPA to keep the airway open. Both groups start with pre-oxygenation using pure oxygen at 30 Lmin for one minute before sedation. The trial involves random assignment to these groups and single masking during the procedure. Participants will be monitored for hypoxia and other respiratory complications during and after the gastroscopy, with evaluations occurring 6 minutes post-procedure. Assessments include the incidence of hypoxia, subclinical respiratory depression, severe hypoxia, airway complications, adverse events, and airway interventions needed. The study also tracks patient comfort and safety. The total participation time includes the gastroscopy and immediate post-procedure monitoring, aiming to improve respiratory management in obese patients undergoing painless gastroscopy.

Nasopharyngeal Airway Combined With Nasal High-flow Oxygen Therapy During Painless Gastroscopy in Obesity Patients