Actively Recruiting
National Active Surveillance Network and Pharmacogenomics of Adverse Drug Reactions in Children
Led by University of British Columbia · Updated on 2026-05-01
7000
Participants Needed
1
Research Sites
1230 weeks
Total Duration
On this page
Sponsors
U
University of British Columbia
Lead Sponsor
G
Genome Canada
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of the study is (1) to identify and collect samples from children and adults who take drugs and have adverse drug reactions AND children and adults who take drugs and do not experience any adverse drug effects; (2) to determine if genetic differences between the two groups contribute to causing the adverse drug reactions; and (3) to develop patient specific drug dosing guidelines to prevent future adverse drug reactions. We also wish to compare the use of prescription drugs, medical and hospital services and vital statistics between BC participants who experience adverse drug reactions and those who do not. Study hypothesis: Genetic differences may contribute to patients' response to drugs and may be responsible for adverse drug reactions.
CONDITIONS
Official Title
National Active Surveillance Network and Pharmacogenomics of Adverse Drug Reactions in Children
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Children under 19 years who have taken drugs
- Biological parents of children who have had an adverse drug reaction
- Patients or parents who speak and understand English (except in Quebec)
- Adults participating for validation of findings in children
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Children's and Women's Health Centre of British Columbia
Vancouver, British Columbia, Canada, V6H 3V4
Actively Recruiting
Research Team
B
Bruce Carleton, PharmD.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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