Study on How Environmental Factors Affect Human Health and Injury in Adults

What this Trial Is About

Researchers are exploring how environmental factors like pollution, diet, and stress contribute to human diseases and inflammation. The study aims to understand how these exposures cause injury and affect disease development by examining interactions between individuals and their environment. This observational study focuses on healthy adults aged 18 to 90 years and seeks to develop improved methods for measuring these host-environment interactions. Participants in this study may provide a variety of biological and environmental samples, including blood, hair, stool, saliva, urine, skin cells, nail clippings, exhaled breath, sputum, nasal cells, cheek cells, and sperm samples if applicable. Some participants may undergo procedures like bronchoscopy or pelvictransvaginal ultrasound and perform lung function tests. Samples of household dust, urine, or stool may also be collected at home. Participants will complete surveys about their health, diet, and environmental exposures. During the study, participants will be screened using health history questions and demographic information. The study may involve one or more visits, during which samples and data are collected. Researchers will analyze biological markers related to cell injury and inflammation, such as inflammatory cytokines and DNARNA damage, to better understand environmental impacts on health. Participants may be contacted later for involvement in other studies, with the total participation time varying by individual.

Natural History of the Human Biological Response to Environmental Exposure and Injury