Actively Recruiting

Age: 6Months +
All Genders
NCT06563414

A Natural History Study of Corneal Abrasions in Patients With Dystrophic Epidermolysis Bullosa (DEB)

Led by Krystal Biotech, Inc. · Updated on 2025-07-02

40

Participants Needed

1

Research Sites

69 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study is a non-interventional, observational study that will evaluate the natural history of corneal abrasions in patients with Dystrophic Epidermolysis Bullosa (DEB).

CONDITIONS

Official Title

A Natural History Study of Corneal Abrasions in Patients With Dystrophic Epidermolysis Bullosa (DEB)

Who Can Participate

Age: 6Months +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • The subject or their legal guardian must have read, understood, and signed an Institutional Review Board (IRB) approved Informed Consent/Assent Form and be able and willing to follow study procedures and instructions.
  • Age 6 months or older at time of Informed Consent/Assent.
  • Prior genetic diagnosis of DEB due to mutation(s) in the collagen type VII alpha 1 chain (COL7A1) gene.
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

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Trial Site Locations

Total: 1 location

1

Krystal Biotech

Pittsburgh, Pennsylvania, United States, 15203

Actively Recruiting

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Research Team

D

David Chien, MD

CONTACT

B

Brittani Agostini, RN, CCRC

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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