Actively Recruiting
Natural History Study of Usher Syndrome ( Light4Deaf )
Led by Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts · Updated on 2020-12-14
400
Participants Needed
4
Research Sites
521 weeks
Total Duration
On this page
Sponsors
C
Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Lead Sponsor
A
Assistance Publique - Hôpitaux de Paris
Collaborating Sponsor
AI-Summary
What this Trial Is About
Clinical centres in the LIGHT4DEAF consortium have developed and will continue to improve a reliable, early molecular diagnosis and protocols for full clinical characterisation of Usher syndrome, which will be valuable for the foreseen USH clinical trials. The clinical arm of the project aims at performing a deep-phenotyping of retinal degeneration, hearing loss, vestibular dysfunction, neurocognitive ability of subects with a molecular diagnosis of any Usher syndrome. Functional and structural parameters for retinal, auditory, and vestibular impairments are followed overtime to document the natural history of the disease and establish relevant clinical endpoint for disease progression that may be useful for future clinical trials.
CONDITIONS
Official Title
Natural History Study of Usher Syndrome ( Light4Deaf )
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient with a molecular diagnosis of Usher syndrome type I, II or III or a clinical diagnosis of Usher syndrome type I, II or III which will then be confirmed by a molecular diagnosis
- Health insurance beneficiary
- Informed consent signed by the patient or their legal representatives
You will not qualify if you...
- Patient or his/her legal representatives unable to understand the study and for whom informed consent cannot be obtained
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 4 locations
1
Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Paris, France, 75012
Actively Recruiting
2
CHU Pitié Salpêtrière
Paris, France, 75013
Actively Recruiting
3
CHU Necker
Paris, France, 75015
Actively Recruiting
4
CHU Robert Debré
Paris, France, 75019
Actively Recruiting
Research Team
I
Isabelle AUDO, Pr
CONTACT
T
Thilissa DIB
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here