Actively Recruiting
Navigate - Improving Survival and Quality of Life in Vulnerable Lung Cancer Patients
Led by Zealand University Hospital · Updated on 2025-12-29
250
Participants Needed
6
Research Sites
252 weeks
Total Duration
On this page
Sponsors
Z
Zealand University Hospital
Lead Sponsor
D
Danish Cancer Society
Collaborating Sponsor
AI-Summary
What this Trial Is About
Half of patients with lung cancer face a limited life span of one-year survival, which is characterized by severe physical and psychological symptoms. Differences in stage, comorbidity but also treatment may explain a large proportion of the social inequality in lung cancer survival. Some vulnerable patients may not receive first line treatment as planned either due to poor performance status or if they are not able to adhere to treatment appointments. Knowing how to navigate the health system may be a barrier preventing vulnerable patients in receiving optimal treatment. The primary aim of this randomised, controlled trial is to test whether a nurse-led individually tailored program including systematic screening of symptoms using PROs and a physical training program will significantly improve a composite outcome of survival and quality of life as the primary outcome among vulnerable lung cancer patients compared with standard care. Secondary outcomes include adherence to cancer treatment, symptom burden and overall survival.
CONDITIONS
Official Title
Navigate - Improving Survival and Quality of Life in Vulnerable Lung Cancer Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Diagnosed with non-small cell lung cancer at any stage regardless of treatment intention
- Performance status 2 or less
- Classified as vulnerable according to predefined criteria
You will not qualify if you...
- Severe untreated psychiatric disorder or cognitive problems preventing informed consent
- Unable to receive treatment
- Unable to read and understand Danish
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 6 locations
1
Aalborg University Hospital
Aalborg, Denmark
Actively Recruiting
2
Gødstrup Hospital
Herning, Denmark
Actively Recruiting
3
Odense University Hospital
Odense, Denmark
Actively Recruiting
4
Zealand University Hospital
Roskilde, Denmark
Actively Recruiting
5
Sønderborg Sygehus
Sønderborg, Denmark
Actively Recruiting
6
Vejle Sygehus
Vejle, Denmark
Actively Recruiting
Research Team
R
Rikke Langballe, PhD
CONTACT
R
Randi V Karlsen, MEd
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here