Actively Recruiting
NE3107 in Adults With Neurological Symptoms of Long COVID
Led by BioVie Inc. · Updated on 2026-02-19
208
Participants Needed
20
Research Sites
65 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Long COVID is a condition where debilitating symptoms can persist for months after a COVID-19 infection. This study aims to evaluate the effects of NE3107 on several neurological symptoms reported in people with Long COVID including difficulty concentrating or remembering things ("brain fog") and fatigue. Researchers will compare NE3107 to a placebo (a look-alike substance that contains no drug) to see if NE3107 works to treat neurocognitive and fatigue symptoms of long COVID. Participants will: * Take NE3107 or a placebo twice daily for 84 days * Visit the clinic 5 times for checkups and tests and have a follow up phone call
CONDITIONS
Official Title
NE3107 in Adults With Neurological Symptoms of Long COVID
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 to 69 years
- Long COVID with neurological symptoms including fatigue and neurocognitive impairment starting or worsening after a COVID-19 infection at least 3 months before screening
- Symptoms lasting for at least 3 months
- Symptoms not explained by other conditions as judged by the investigator
- Agree to keep other regular medications at current doses during the study unless medically necessary to change
- Agree to use birth control methods
- Provide voluntary consent
- Willing to allow blood collection
- Pass all screening tests and procedures
You will not qualify if you...
- Received a COVID-19 vaccination within 14 days prior to screening
- Previous admission to intensive care unit for COVID-19
- History of major mental or physical illness before COVID-19 infection
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 20 locations
1
Stanford University
Palo Alto, California, United States, 94304
Actively Recruiting
2
UCSF
San Francisco, California, United States, 94110
Actively Recruiting
3
University of Colorado
Aurora, Colorado, United States, 80045
Actively Recruiting
4
Yale University
New Haven, Connecticut, United States, 06519
Actively Recruiting
5
Clinical Trial Site
Jacksonville, Florida, United States, 32258
Actively Recruiting
6
Centricity Research
Columbus, Georgia, United States, 31904
Actively Recruiting
7
Illinois Research Network University of Illinois at Chicago
Chicago, Illinois, United States, 60608
Actively Recruiting
8
Northwestern University
Chicago, Illinois, United States, 60611
Actively Recruiting
9
University of Iowa
Iowa City, Iowa, United States, 52242
Actively Recruiting
10
Norton Infectious Disease Institute
Louisville, Kentucky, United States, 40202
Actively Recruiting
11
Jadestone Clinical Research
Silver Spring, Maryland, United States, 20904
Actively Recruiting
12
Clinical Trial Site
Farmington Hills, Michigan, United States, 48334
Actively Recruiting
13
Mayo Clinic
Rochester, Minnesota, United States, 55905
Actively Recruiting
14
Icahn School of Medicine at Mount Sinai
New York, New York, United States, 10029
Actively Recruiting
15
University Hospitals Cleveland Medical Center
Cleveland, Ohio, United States, 44106
Actively Recruiting
16
Zenos Clinical Research
Dallas, Texas, United States, 75230
Actively Recruiting
17
University of Texas health Science Center at San Antonio
San Antonio, Texas, United States, 78229
Actively Recruiting
18
Chronicle Bio Inc.
Park City, Utah, United States, 84119
Actively Recruiting
19
Swedish Center for Research and Innovation
Seattle, Washington, United States, 98104
Actively Recruiting
20
West Virginia University
Morgantown, West Virginia, United States, 26506
Actively Recruiting
Research Team
P
Penelope Markham, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here