Actively Recruiting
A Near-Infrared Functional Imaging Study on Motor Imagery Training in Patients With Spinal Cord Injury
Led by Shengjing Hospital ยท Updated on 2025-08-06
36
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the use of motor imagery-based brain-computer interface (MI-BCI) technology to improve motor function in patients with spinal cord injury (SCI). This study aims to assess how MI-BCI affects motor recovery and cortical motor area function during different states, such as resting and task performance. The trial compares MI-BCI with active cycling training as a conventional rehabilitation control to explore new strategies for SCI rehabilitation. Participants will be randomly assigned to either an experimental group receiving MI-BCI training or a control group undergoing cycling training. Both groups will use an EEG-based rehabilitation device (L-B300) with sessions lasting 20 minutes, five days a week, for four weeks. The MI-BCI group will perform guided motor imagery tasks using the device, while the cycling group will experience passive or active cycling motions with the device. Throughout the study, participants will be evaluated at baseline, two weeks, and four weeks for lower limb motor function, daily living activities, walking ability, and brain activity using functional near-infrared spectroscopy (fNIRS) and electroencephalography (EEG). Assessments are conducted by trained professionals unaware of group assignments, and the study includes a total of 20 treatment sessions. The primary outcome measures focus on motor function improvements and changes in cortical motor area function.
CONDITIONS
Brief Title
Near-Infrared Imaging of Motor Imagery Effects in Spinal Cord Injury
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Vital signs are stable and spine is stable, suitable for exercise testing
- Diagnosed spinal cord injury (SCI) by CT or MRI meeting 2019 American SCI Society criteria
- Injury level between C5 and T12 with ASIA grade A, B, or C
- Disease duration 12 months or less, with spinal shock period passed
- Age between 18 and 75 years, any gender
- Good cognitive function, able to understand and participate, and willing to sign informed consent
You will not qualify if you...
- Presence of tumors, tuberculosis, blood diseases, or important organ dysfunction such as heart or liver
- Unstable fractures
- Severe abnormal limb muscle tone or joint contracture deformities
- Severe pain that prevents tolerating activities
- Severe emotional problems preventing cooperation to complete the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 4 weeks
Participants will undergo EEG-based rehabilitation training or cycling training using the L-B300 device. Group A will perform motor imagery training with device assistance, while Group B will undergo passive or active cycling movements. Both groups participate in 20-minute sessions, 5 days per week, for 4 weeks.
20 sessions (in-person, 5 days per week)
Duration - 4 weeks
Participants will have motor function and brain activity assessments at baseline, 2 weeks, and 4 weeks post-treatment, including the ASIA Impairment Scale, Modified Barthel Index, and brain imaging with fNIRS and EEG.
3 visits (in-person) at baseline, 2 weeks, and 4 weeks
Trial Site Locations
Total: 1 location
1
Rehabilitation Center of Shengjing Hospital, China Medical University
Shenyang, Liaoning, China
Actively Recruiting
Research Team
X
Xue Jiang
H
He Xiao Gao
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here