Actively Recruiting
Neck Observation or Elective Neck Dissection in CT1N0M0 OSCC
Led by Huashan Hospital · Updated on 2024-11-14
300
Participants Needed
1
Research Sites
209 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To evaluate the clinical outcomes of 2-year lymph node metastasis rate, disease-free survival, overall survival, and health-related quality of life in the patients with cT1N0M0 oral squamous cell carcinoma, who receive primary lesion resection combined with elective neck dissection or primary lesion resection only.
CONDITIONS
Official Title
Neck Observation or Elective Neck Dissection in CT1N0M0 OSCC
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Tumor located in tongue, gingiva, buccal mucosa, floor of mouth, hard palate, or retromolar area
- Clinical stage is cT1N0M0 according to AJCC 8th edition
- Pathological diagnosis of squamous cell carcinoma
- Signed informed consent form
You will not qualify if you...
- More than 2 lesions in the oral cavity
- History of malignant tumor within the past 5 years unless fully treated and no recurrence
- Previous unilateral or bilateral neck dissection
- Prior head and neck radiotherapy
- Pregnant or lactating women
- Severe uncontrolled infection, known HIV infection, or history of organ, stem cell, or bone marrow transplant
- Participation in another clinical study within 30 days before enrollment
- Other conditions deemed unsuitable by the researcher
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Huashan Hospital, Fudan University
Shanghai, China, 200040
Actively Recruiting
Research Team
L
Lai-ping Zhong, MD, PhD
CONTACT
L
Liang Gu, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here