Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
Healthy Volunteers
NCT05321316

Nectin-4 Specific LMW PET Probe Imaging in Urothelial Carcinoma

Led by Peking University Cancer Hospital & Institute · Updated on 2026-03-04

20

Participants Needed

1

Research Sites

26 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To evaluate the ability of \[68Ga\]N188 to detect nectin-4 overexpression in patients with urothelial carcinoma, especially in patients with recurrent or advanced bladder cancer.

CONDITIONS

Official Title

Nectin-4 Specific LMW PET Probe Imaging in Urothelial Carcinoma

Who Can Participate

Age: 18Years - 75Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 75 years, male or female
  • Normal heart function
  • Estimated survival of at least 12 weeks
  • Good compliance with follow-up
  • At least one measurable target lesion according to RECIST 1.1 criteria
  • Women of childbearing age (15-49 years) must have a negative pregnancy test within 7 days before starting the test
  • Fertile men and women must agree to use effective contraception during the study and for 3 months after
  • Recommended by clinicians for PET/CT tumor diagnostic staging
  • Able to understand and voluntarily consent to participate
Not Eligible

You will not qualify if you...

  • Serious abnormalities of liver, kidney, or blood
  • Pregnant patients
  • Pregnant or lactating women
  • Unable to lie flat for half an hour
  • Refusal to participate
  • Claustrophobia or other mental diseases
  • Other conditions deemed unsuitable by researchers

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Beijing Cancer Hospital

Beijing, Beijing Municipality, China, 100142

Actively Recruiting

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Research Team

Z

Zhi Yang, Professor

CONTACT

H

Hua Zhu, Professor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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