Actively Recruiting

Age: 18Years - 65Years
All Genders
NCT06373003

Negative Antiphospholipid Syndrome: a Multicentric Study

Led by Italian Society for Rheumatology · Updated on 2025-05-14

105

Participants Needed

1

Research Sites

101 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Multicentre no-profit, national, (cross-sectional diagnostic) retrospective study, promoted by the Italian Society for Rheumatology. The main objective of the study is to assess the diagnostic accuracy of non-criteria aPL (anti-vimentin/cardiolipin and anti-phosphatidylserine/prothrombin) in identifying APS in patients with thrombosis/recurrent adverse pregnancy outcomes.

CONDITIONS

Official Title

Negative Antiphospholipid Syndrome: a Multicentric Study

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients fulfilling the classification criteria for antiphospholipid syndrome (seropositive APS)
  • Patients with seronegative APS (SN-APS) having clinical criteria for APS, persistently negative for aPL, and highly suggestive clinical features
  • Patients with clinical criteria for APS, negative for aPL, without highly suggestive clinical features
  • Age under 65 years at time of event
  • Less than 5 years since the first event
Not Eligible

You will not qualify if you...

  • Patients in groups 2 and 3 with a known cause of thrombosis or obstetrical problems
  • Deceased patients
  • Patients with 5 or more years since their first event

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Umberto I Polyclinic, Rome- Department of Rheumatology

Roma, Rome, Italy, 00185

Actively Recruiting

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Research Team

F

Fabrizio Conti, MD

CONTACT

S

Simona Truglia, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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Negative Antiphospholipid Syndrome: a Multicentric Study | DecenTrialz