Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
NCT06602843

Neoadjuvant Chemoimmunotherapy Followed by Surgery and Postoperative Radioimmunotherapy

Led by Anhui Provincial Hospital · Updated on 2024-09-19

70

Participants Needed

1

Research Sites

156 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this study was to explore the efficacy and safety of neoadjuvant chemoimmunotherapy followed by surgery and postoperative radioimmunotherapy in patients with locally advanced esophageal squamous cell carcinoma

CONDITIONS

Official Title

Neoadjuvant Chemoimmunotherapy Followed by Surgery and Postoperative Radioimmunotherapy

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Ages 18-75
  • Radical operation for esophageal cancer
  • Esophageal squamous cell carcinoma confirmed by postoperative pathology
  • Preoperative imaging and postoperative pathology stage pIIB-IVA (AJCC eighth edition): T≥3 or N+
  • At least 12 lymph nodes surgically removed
  • Postoperative ECOG score 0-1, able to tolerate postoperative adjuvant radiotherapy and immunotherapy
  • Informed consent signed by patient or family member
Not Eligible

You will not qualify if you...

  • Younger than 18 years or older than 75 years
  • Did not receive radical resection of esophageal cancer, including palliative resection
  • Postoperative pathology shows non-esophageal squamous cell carcinoma
  • Stage pI, IIA, or IVB after preoperative imaging and postoperative pathology (AJCC eighth edition)
  • Fewer than 12 lymph nodes surgically removed
  • Postoperative ECOG score 2-3, unable to tolerate postoperative adjuvant radiotherapy and immunotherapy
  • Patient or family member did not sign informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Anhui provincial hospital

Hefei, China

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

2

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