Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
FEMALE
NCT05992870

Neoadjuvant Radiotherapy and Immediate Implant-Based Breast Reconstruction

Led by Hubei Cancer Hospital · Updated on 2025-03-17

40

Participants Needed

1

Research Sites

120 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Neoadjuvant radiotherapy(NART) followed by mastectomy and immediate DIEP flap reconstruction is feasible and technically safe. However, reports of NACT followed immediate implant-based breast reconstruction are rare. Some studies have shown that NART followed immediate implant-based breast reconstruction seems feasible and can be safely attempted. It's well known that radiotherapy after implant-based breast reconstruction have negative effects on implant and cosmetic results. So, investigators conducted a polit study to learn about acute post-surgical complications following skin-sparing mastectomy and immediate implant-based breast reconstruction after NART.

CONDITIONS

Official Title

Neoadjuvant Radiotherapy and Immediate Implant-Based Breast Reconstruction

Who Can Participate

Age: 18Years - 75Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Women over 18 years with confirmed breast cancer
  • Require mastectomy for any reason
  • Have a known indication for radiotherapy
  • Need implant-based breast reconstruction
Not Eligible

You will not qualify if you...

  • Unable to give informed consent
  • Multidisciplinary team cannot recommend radiotherapy based on preoperative findings
  • Previous breast cancer or other cancer requiring breast or axilla radiotherapy
  • Pregnant or lactating
  • Have inflammatory breast cancer

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Xinhong Wu

Wuhan, Hubei, China, 430079

Actively Recruiting

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Research Team

X

Xinhong Wu, MD

CONTACT

N

Ning Zou, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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