Actively Recruiting

Age: 0Days - 28Days
All Genders
NCT07434596

Neonatal Intestinal Obstruction: Prenatal Factors and Postnatal Outcomes

Led by Meyer Children's Hospital IRCCS · Updated on 2026-02-25

60

Participants Needed

1

Research Sites

90 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Neonatal intestinal obstruction is one of the most common surgical emergencies in newborns. In some cases, signs of possible intestinal obstruction can already be detected during pregnancy through prenatal ultrasound. However, not all prenatal ultrasound findings accurately predict whether a newborn will truly have an intestinal obstruction after birth. The purpose of this retrospective observational study is to evaluate which prenatal ultrasound findings are most strongly associated with confirmed intestinal obstruction after birth. In particular, the study aims to identify a specific cutoff value for fetal bowel dilation that best predicts postnatal intestinal obstruction. Other prenatal ultrasound features, such as excess amniotic fluid (polyhydramnios), ascites, echogenic bowel, and other abdominal findings, will also be analyzed. The study will include newborns with a prenatal suspicion of intestinal obstruction who were evaluated at Meyer Children's Hospital between January 2016 and December 2024. Researchers will review existing medical records and ultrasound data. No additional tests or interventions will be performed for study purposes. The results of this study may help improve prenatal counseling, optimize delivery planning in specialized centers, and support early postnatal management of newborns at risk for intestinal obstruction.

CONDITIONS

Official Title

Neonatal Intestinal Obstruction: Prenatal Factors and Postnatal Outcomes

Who Can Participate

Age: 0Days - 28Days
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Neonates from singleton pregnancies with prenatal ultrasound suspicion of intestinal obstructive pathology
  • Availability of complete postnatal follow-up data
Not Eligible

You will not qualify if you...

  • Missing delivery data
  • Missing prenatal ultrasound data

AI-Screening

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Trial Site Locations

Total: 1 location

1

Aou Meyer IRCSS

Florence, Florence, Italy, 50139

Actively Recruiting

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Research Team

A

Antonino Morabito

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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