Actively Recruiting

Phase Not Applicable
Age: 1Minute - 15Minutes
All Genders
NCT04225975

Neonate Cerebral Activity in Immediate Post Partum

Led by Centre Hospitalier Universitaire, Amiens · Updated on 2026-05-13

60

Participants Needed

1

Research Sites

304 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Neonatal anoxia-ischemia causes significant neurodevelopmental disorders. In this study the investigators want to better understand the interactions between the nervous and the hemodynamic cerebral systems during the adaptation of the neonate to ectopic life just after birth. Birth is an at risk situation of neonatal anoxic ischemia and the lack of objective criteria for cerebral tissue oxygenation has consequences on neuronal activity. Ph cord analysis is inadequate and only indirectly reflects the state of cerebral oxygenation. Both neuronal and vascular systems are part of the same functional entity and the analysis of their interactions is likely to reveal some early malfunctions of these networks. In this study, the investigators want to develop a multi-scale, multimodal approach that allows simultaneous interrogation of both neuronal and vascular compartments during the 15 minutes after delivery. The investigators will record, with the aid of a single sensor placed on the scalp of the child, the electroencephalogram and the cerebral tissue oxygenation. The investigators will measure interactions by means of correlation analysis between both signals.

CONDITIONS

Official Title

Neonate Cerebral Activity in Immediate Post Partum

Who Can Participate

Age: 1Minute - 15Minutes
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Full term neonates between 36 and 41 weeks Gestational Age
Not Eligible

You will not qualify if you...

  • Premature neonates
  • Neonates of twin pregnancy
  • Suspicion of congenital malformation seen in antenatal ultrasound
  • Any pathology requiring pediatric care from birth
  • Newborns whose mothers had a chronic viral infection such as AIDS, hepatitis B or C, or who had a multidrug-resistant bacteria

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

CHU Amiens

Amiens, France, 80054

Actively Recruiting

Loading map...

Research Team

F

Fabrice Wallois, Pr

CONTACT

J

Jean Gondry, Pr

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

SCREENING

Number of Arms

0

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here