Actively Recruiting

Phase Not Applicable
Age: 1Minute - 15Minutes
All Genders
ID04225975

Evaluation of Cerebral, Hemodynamic and Neuronal Activities in Neonates in the Immediate Postpartum

Led by Centre Hospitalier Universitaire, Amiens · Updated on 2026-05-13

60

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying how the brain's nervous and blood flow systems interact in newborns right after birth, focusing on neonates at risk of oxygen deprivation and brain injury. This research aims to improve understanding of cerebral oxygenation and neuronal activity during this critical transition period. The study targets full-term neonates between 36 and 41 weeks gestational age and monitors brain function immediately after delivery to detect early signs of problems. The study uses a single sensor placed on the newborn's scalp within five minutes after birth to record two key signals: the brain's electrical activity via electroencephalogram (EEG) and cerebral tissue oxygen levels using oxymetry. These signals will be analyzed simultaneously to examine their correlation over time and frequency, aiming to reveal how the brain and blood flow systems work together during those first crucial minutes after birth. Participants will have EEG and cerebral oxygenation recorded during the first five minutes post-delivery. Researchers will analyze how these signals correlate and assess any relation to the mode of delivery. The study involves no masking or randomization, focusing on detailed measurements during this immediate postpartum window. The total participation is brief, centered on the initial minutes after birth, with ongoing data analysis to identify potential early brain malfunctions.

CONDITIONS

Brief Title

Neonate Cerebral Activity in Immediate Post Partum

Who Can Participate

Age: 1Minute - 15Minutes
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Full term neonates between 36 and 41 weeks Gestational Age
Not Eligible

You will not qualify if you...

  • Premature neonates
  • Neonates of twin pregnancy
  • Suspicion of congenital malformation seen in antenatal ultrasound
  • Any pathology requiring pediatric care from birth
  • Newborns whose mothers had a chronic viral infection such as AIDS, hepatitis B or C, or who had a multidrug-resistant bacteria

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Within 5 minutes after birth

Participants undergo recording of cerebral activity using electroencephalogram and cerebral oxymetry within 5 minutes after birth.

1 visit (in-person)

Trial Site Locations

Total: 1 location

1

CHU Amiens

Amiens, France, 80054

Actively Recruiting

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Research Team

F

Fabrice Wallois, Pr

J

Jean Gondry, Pr

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

SCREENING

Number of Arms

0

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