Actively Recruiting
Does Nerve Block + Oral Dexamethasone Reduce Recurrence of Headache Within 72 Hrs?
Led by Texas Tech University Health Sciences Center, El Paso · Updated on 2026-05-06
84
Participants Needed
1
Research Sites
228 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
For some patients who come to the emergency department for treatment of a migraine headache, peripheral headache nerve blocks (PHNB) have proven to be an efficient and effective treatment for headache relief. Previous studies have demonstrated that adding steroids as an adjunct treatment to standard migraine treatment can reduce recurrence of headaches in the subsequent few days.
CONDITIONS
Official Title
Does Nerve Block + Oral Dexamethasone Reduce Recurrence of Headache Within 72 Hrs?
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Meet ICHD-3 Migraine Headache Criteria
- Had a minimum 5-point reduction in headache intensity after nerve block(s) or post-block pain score of 0 to 2
- Nerve block performed with bupivacaine 0.5%
You will not qualify if you...
- Head trauma
- Suspicion of secondary headache such as stroke, known tumor, or glaucoma
- Headache in the setting of viral syndrome
- Chronically on steroids
- Known allergy to dexamethasone
- Unable to reach the patient by phone or text for follow-up
- Gestational diabetes or other uncontrolled diabetes
- Known to be immunocompromised
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University Medical Center of El Paso
El Paso, Texas, United States, 79905
Actively Recruiting
Research Team
E
Edward Michelson, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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