Actively Recruiting
Neural Bases of Decision-making in Healthy Individuals
Led by Istituti Clinici Scientifici Maugeri SpA · Updated on 2026-05-08
150
Participants Needed
1
Research Sites
468 weeks
Total Duration
On this page
Sponsors
I
Istituti Clinici Scientifici Maugeri SpA
Lead Sponsor
I
Istituto Universitario di Studi Superiori Pavia
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this single center non-interventional fMRI study is to assess the neural bases of decision-making and executive functioning in healthy individuals,and whether/how their responsiveness is modulated by ageing. The main questions it aims to answer are: 1. are there specific neural correlates for ageing effects on executive functioning (particularly inhibitory control) and decision-making? 2. Is there a relationship, at the behavioral and neural levels, between ageing-related changes in executive functioning and decision-making? Healthy participants will be recruited for 1. a behavioral assessment including multiple tests of decision-making and executive functioning/inhibitory control; 2. a fMRI session to collect data concerning a) brain activity associated with decision-making and executive functioning, b) brain structural morphometriy (grey-matter volume/density), and c) brain structural connectivity (diffusion weighted imaging). Results will provide an useful baseline for investigating alterations of decision-making and executive functioning, and of their neural bases, in pathological conditions.
CONDITIONS
Official Title
Neural Bases of Decision-making in Healthy Individuals
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy participants as determined by screening and investigator judgment
- Ability to comply with study requirements as judged by the principal investigator
You will not qualify if you...
- History of alcohol or drug abuse, addiction, or regular use of drugs of abuse
- Use of psychoactive medications or medications affecting the central nervous system or blood flow
- Contraindications to MRI or brain/head abnormalities preventing MRI eligibility
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Istituti Clinici Scientifici Maugeri SpA
Pavia, Ita, Italy, 27100
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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