Actively Recruiting
Neural Bases of Social Cognitive Processing in Healthy Individuals
Led by Istituti Clinici Scientifici Maugeri SpA · Updated on 2026-05-08
200
Participants Needed
1
Research Sites
485 weeks
Total Duration
On this page
Sponsors
I
Istituti Clinici Scientifici Maugeri SpA
Lead Sponsor
I
Istituto Universitario di Studi Superiori Pavia
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this single center non-interventional fMRI and EEG study is to assess the neural bases of social cognitive processing in healthy individuals, and whether/how their responsiveness is modulated by ageing. The main questions it aims to answer are: * are there specific brain regions where individual differences in social cognitive performance reflect well-established metrics of social cogntion such as empathy and mentalizing? * is there a relationship, at the behavioral and neural levels, between ageing-related changes in social cognitive performance and empathy/mentalizing? Healthy participants will be recruited for: * a behavioral assessment including multiple tests of social cognition focused on empathy and mentalizing; * for half participants: a fMRI session to collect data concerning a) brain activity associated with action observation and social cognitive processing, b) brain structural morphometriy (grey-matter volume/density), and c) brain structural connectivity (diffusion weighted imaging) * for half participants: a EEG session to collect data concerning brain responsiveness to social cognitive processing with higher temporal resolution than that afforded by fMRI. Results will provide an useful baseline for investigating alterations of social cognitive processing, and of their neural bases, in pathological conditions.
CONDITIONS
Official Title
Neural Bases of Social Cognitive Processing in Healthy Individuals
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy participants as determined by screening and investigator judgment
- Ability to comply with study requirements as judged by the principal investigator
You will not qualify if you...
- History of alcohol or drug abuse, addiction, or regular drug use
- Use of psychoactive medications or drugs affecting the central nervous system or blood flow
- Contraindications for MRI or brain/head abnormalities preventing MRI eligibility
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Istituti Clinici Scientifici Maugeri SpA
Pavia, Ita, Italy, 27100
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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