Actively Recruiting

Age: 18Years - 70Years
All Genders
ID06764290

Neural Mechanism Changes in Stroke Patients During Challenging Walking Tasks Observing Brain Activity with Pedal Walking and Visual Occlusion

Led by Nanjing Medical University · Updated on 2025-01-08

60

Participants Needed

2

Research Sites

47 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to explore the neural and biomechanical changes in stroke patients during challenging walking tasks that may help stimulate brain recovery. The study focuses on stroke patients who have experienced their first stroke, with the condition confirmed by imaging and clinical diagnosis, and who can walk independently despite abnormal gait patterns. Researchers are investigating how difficult tasks like pedal walking and walking with eyes covered affect brain activation. Participants will wear a 32-lead electroencephalogram (EEG) cap to record brain activity while performing three walking tasks: walking on a flat surface for 60 seconds, resting for 2 minutes, then walking on a pedal for 60 seconds, resting again for 2 minutes, and finally walking with their eyes covered for 60 seconds. Pedal walking and walking with eyes covered are both considered challenging tasks and are being studied as potential physical therapy methods. During the study, participants' brain activity will be monitored using the EEG cap to measure outcomes such as Weight Phase Lag Index and relative power over 60-second intervals. The study is observational and cross-sectional, collecting data simultaneously as the trials occur. Researchers will assess neural responses to these walking tasks to better understand brain recovery mechanisms after stroke.

CONDITIONS

Official Title

Neural Changes in Stroke Patients During Challenging Walking Tasks.

Who Can Participate

Age: 18Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • First-time stroke confirmed by computed tomography or magnetic resonance imaging and clinical diagnosis
  • Stroke disease duration more than 14 days and less than 1 year
  • Able to walk independently but with a lingering abnormal gait
Not Eligible

You will not qualify if you...

  • Lesions accumulate in the brainstem
  • Lesions accumulate in the cerebellum
  • Impaired vision
  • Severe cognitive impairment

AI-Screening

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Trial Site Locations

Total: 2 locations

1

Geriatric Hospital of Nanjing Medical University, 269 Qingmen Street

Nanjing, Jiangsu, China, 210000

Actively Recruiting

2

Geriatric Hospital of Nanjing Medical University

Nanjing, Jiangsu, China, 210000

Actively Recruiting

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Research Team

J

Jing Zhao, master

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

Frequently Asked Questions

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