Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT06074614

Neural Control of Breathing in Parkinson's Disease

Led by Radboud University Medical Center · Updated on 2024-12-20

30

Participants Needed

1

Research Sites

78 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Breathing is a complex process, which can be controlled through voluntary command or neural control. Parkinson's disease (PD) is a progressive neurological disorder. Many individuals with PD experience respiratory problems, such as coughing difficulties or shortness of breath. Changes in neural control of breathing could be part of the reason of these respiratory problems. This study will measure whether neural control of breathing is impaired in individuals with PD compared to healthy individuals.

CONDITIONS

Official Title

Neural Control of Breathing in Parkinson's Disease

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy adults older than 18 years
  • Patients with Parkinson's disease, clinically confirmed by a movement disorder neurologist, with Hoehn and Yahr stage 1 to 3
  • Willingness and ability to understand the study and participate
  • Ability to comply with study requirements
Not Eligible

You will not qualify if you...

  • Healthy subjects with past or current central nervous system diseases
  • Patients with central nervous system diseases other than Parkinson's disease
  • History or current psychiatric treatment
  • History or current brain surgery, epilepsy, or deep brain stimulation
  • Neuromuscular disorders
  • Pre-existing lung diseases such as COPD, asthma, or pulmonary fibrosis
  • Incompatibility with transcranial magnetic stimulation (metal in head/neck, skin allergies)
  • Implanted devices like pacemakers, neurostimulators, cochlear implants, or infusion devices
  • Large or ferromagnetic metal parts in the head except dental wires
  • Pregnancy
  • Smoking

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Radboudumc

Nijmegen, Gelderland, Netherlands, 6500 HB

Actively Recruiting

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Research Team

J

Jonne Doorduin, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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